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  1. Article

    Open Access

    A novel reverse transduction adenoviral array for the functional analysis of shRNA libraries

    The identification of novel drug targets by assessing gene functions is most conveniently achieved by high-throughput loss-of-function RNA interference screening. There is a growing need to employ primary cell...

    Angelika Oehmig, Andrea Klotzbücher, Maria Thomas, Frank Weise in BMC Genomics (2008)

  2. No Access

    Chapter

    Mdm2 and ARF

    One of the major defense mechanisms against the development of cancer is governed by the tumor-suppressor protein p53. The p53 protein can induce growth arrest and apoptosis, and, owing to these important func...

    Andrea Klotzbücher, Michael H. G. Kubbutat in Targets for Cancer Chemotherapy (2002)