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Article
Open AccessCorrection to: Recommendation of RILEM TC 264 RAP on the evaluation of asphalt recycling agents for hot mix asphalt
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Article
Open AccessRNA aptamers specific for transmembrane p24 trafficking protein 6 and Clusterin for the targeted delivery of imaging reagents and RNA therapeutics to human β cells
The ability to detect and target β cells in vivo can substantially refine how diabetes is studied and treated. However, the lack of specific probes still hampers a precise characterization of human β cell mass...
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Article
Open AccessFatal cytokine release syndrome by an aberrant FLIP/STAT3 axis
Inflammatory responses rapidly detect pathogen invasion and mount a regulated reaction. However, dysregulated anti-pathogen immune responses can provoke life-threatening inflammatory pathologies collectively k...
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Article
Open AccessRecommendation of RILEM TC 264 RAP on the evaluation of asphalt recycling agents for hot mix asphalt
This recommendation is based on the results of an inter-laboratory study organised by the RILEM technical committee TC 264-RAP "Asphalt Pavement Recycling"—Task Group 3 (TG3) focusing on Asphalt Binder for Rec...
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Chapter and Conference Paper
Effect of Aging on the Rheological Properties of Blends of Virgin and Rejuvenated RA Binders
The use of rejuvenators has seen a consistent increase over the years in the asphalt pavement industry. This is due to the need for maximizing the demand for incorporating a higher amount of Reclaimed Asphalt ...
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Chapter and Conference Paper
Experimental Investigation on Water Loss and Stiffness of CBTM Using Different RA Sources
Cold recycling of reclaimed asphalt (RA) is a promising technique to build or to maintain roads, combining performance and environmental advantages. Although this technique has been extensively used worldwide,...
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Article
Open AccessHuman T cells engineered with a leukemia lipid-specific TCR enables donor-unrestricted recognition of CD1c-expressing leukemia
Acute leukemia relapsing after chemotherapy plus allogeneic hematopoietic stem cell transplantation can be treated with donor-derived T cells, but this is hampered by the need for donor/recipient MHC-matching ...
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Article
Single-cell analyses reveal YAP/TAZ as regulators of stemness and cell plasticity in glioblastoma
Glioblastoma (GBM) is a devastating human malignancy. GBM stem-like cells (GSCs) drive tumor initiation and progression. Yet the molecular determinants defining GSCs in their native state in patients remain po...
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Chapter and Conference Paper
Repeatability Study on the Laboratory Production Process of Cement Bitumen Treated Materials with Foamed Bitumen
Cold recycled materials are mixes with high percentages of reclaimed asphalt (RA), while the binding phase is commonly composed of Portland cement and bitumen (emulsion or foam). The reproduction of such mater...
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Chapter and Conference Paper
Influence of Curing on the Mechanical Properties of Cement-Bitumen Treated Materials Using Foamed Bitumen: An Interlaboratory Test Program
The use of reclaimed asphalt (RA) in road pavements is continuously gaining interest thanks to the technical, economic and environmental advantages guaranteed by such sustainable practice. Cold recycling techn...
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Article
Recommendation of RILEM TC237-SIB on fragmentation test for recycled asphalt
This recommendation describes how to characterize the reclaimed asphalt through the fragmentation test. The guidelines given hereafter are based on the results of a round robin test organized by the RILEM Tech...
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Article
Pavement Management System for local administrations: Guidelines in the Republic of San Marino
The Republic of San Marino, located in mid-Italy and looking the Adriatic Sea from the Monte Titano, is one of the smallest and oldest republics in the world. Since 2016, the University of the Republic of San ...
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Article
Recommendation of RILEM TC237-SIB: protocol for characterization of recycled asphalt (RA) materials for pavement applications
This recommendation proposes an experimental protocol to characterize recycled asphalt materials. The guidelines presented in this document are based on the results of a round robin test organized by the RILEM...
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Article
Recommendation of RILEM TC237-SIB on cohesion test of recycled asphalt
This recommendation describes how to evaluate the presence of potentially active bitumen in recycled asphalt (RA) materials through the cohesion test. The experimental protocol is designed according to the res...
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Article
A gene expression signature of Retinoblastoma loss-of-function predicts resistance to neoadjuvant chemotherapy in ER-positive/HER2-positive breast cancer patients
HER2-positive (HER2+) breast cancers show heterogeneous response to chemotherapy, with the ER-positive (ER+) subgroup deriving less benefit. Loss of retinoblastoma tumor suppressor gene (RB1) function has been...
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Article
Open AccessTranscriptional profiling of human bronchial epithelial cell BEAS-2B exposed to diesel and biomass ultrafine particles
Emissions from diesel vehicles and biomass burning are the principal sources of primary ultrafine particles (UFP). The exposure to UFP has been associated to cardiovascular and pulmonary diseases, including lu...
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Chapter
Cold Recycling of Reclaimed Asphalt Pavements
Pavement engineers have in front of them multiple challenges linked to addressing issues related to social development and society’s expanding needs. One of the most substantial of these issues is perhaps how ...
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Article
Open AccessInsulin-like growth factor 1 receptor affects the survival of primary prostate cancer patients depending on TMPRSS2-ERG status
Prostate cancer (PCa) is characterized by clinical and biological heterogeneity and has differential outcomes and mortality rates. Therefore, it is necessary to identify molecular alterations to define new the...
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Article
Volumetric properties and influence of water content on the compactability of cold recycled mixtures
Volumetric characteristics significantly influence the mechanical performance and the durability of bituminous mixtures. Indeed, they are important parameters to be considered in both mix design and quality co...
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Chapter and Conference Paper
Hot Recycling of Reclaimed Asphalt Using a Bio-based Additive
Hot recycling of reclaimed asphalt (RA) has increasing interest worldwide due to economical and environmental benefits. In particular, the use of RA in place of virgin aggregates reduces of aggregate supply an...
