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  1. Article

    Open Access

    The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints

    The immunoreceptor tyrosine-based activation motif (ITAM) pathway provides osteoclast co-stimulatory signals and regulates proliferation, survival and differentiation of effector immune cells. In the osteoclas...

    Tania N Crotti, Anak ASSK Dharmapatni, Ekram Alias… in Arthritis Research & Therapy (2012)

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  2. Article

    Open Access

    TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis

    TNF-like weak inducer of apoptosis (TWEAK) has been proposed as a mediator of inflammation and bone erosion in rheumatoid arthritis (RA). This study aimed to investigate TWEAK and TWEAK receptor (Fn14) express...

    Anak ASSK Dharmapatni, Malcolm D Smith, Tania N Crotti… in Arthritis Research & Therapy (2011)

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  3. Article

    Open Access

    Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium

    Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is a tumour necrosis factor (TNF) family member capable of inducing apoptosis in many cell types.

    Anak ASSK Dharmapatni, Malcolm D Smith, David M Findlay… in Arthritis Research & Therapy (2009)

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