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Article
Open AccessAdaptive immune responses to two-dose COVID-19 vaccine series in healthy Canadian adults ≥ 50 years: a prospective, observational cohort study
To evaluate immune responses to COVID-19 vaccines in adults aged 50 years and older, spike protein (S)-specific antibody concentration, avidity, and function (via angiotensin-converting enzyme 2 (ACE2) inhibit...
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Article
Open AccessFactors associated with SARS-CoV-2 infection in unvaccinated children and young adults
Pediatric COVID-19 cases are often mild or asymptomatic, which has complicated estimations of disease burden using existing testing practices. We aimed to determine the age-specific population seropositivity a...
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Article
Open AccessUptake of SARS-CoV-2 vaccination among structurally-marginalized people who use drugs in Vancouver, Canada
We sought to evaluate the rates and predictors of SARS-CoV-2 vaccination among members of a structurally-marginalized population of people who use drugs (PWUD) during a targeted, community-wide, vaccination ca...
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Article
Open AccessLatent virus infection upregulates CD40 expression facilitating enhanced autoimmunity in a model of multiple sclerosis
Epstein-Barr virus (EBV) has been identified as a putative environmental trigger of multiple sclerosis (MS) by multiple groups working worldwide. Previously, we reported that when experimental autoimmune encep...
