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3 Result(s)

within Amitabha Chaudhuri Remove this filter Science, Humanities and Social Sciences, multidisciplinary Remove this filter

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  1. Article

    Open Access

    Immunodominant T-cell epitopes from the SARS-CoV-2 spike antigen reveal robust pre-existing T-cell immunity in unexposed individuals

    The COVID-19 pandemic has revealed a range of disease phenotypes in infected patients with asymptomatic, mild, or severe clinical outcomes, but the mechanisms that determine such variable outcomes remain unres...

    Swapnil Mahajan, Vasumathi Kode, Keshav Bhojak, Coral Karunakaran… in Scientific Reports (2021)

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  2. Article

    Open Access

    Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate

    Gallbladder cancer (GBC) is an aggressive gastrointestinal malignancy with no approved targeted therapy. Here, we analyze exomes (n = 160), transcriptomes (n = 115), and low pass whole genomes (n = 146) from 167 ...

    Akhilesh Pandey, Eric W. Stawiski, Steffen Durinck, Harsha Gowda… in Nature Communications (2020)

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  3. Article

    Open Access

    A cancer vaccine approach for personalized treatment of Lynch Syndrome

    Lynch syndrome (LS) is a cancer predisposition disorder wherein patients have a 70–80% lifetime risk of develo** colorectal cancers (CRC). Finding germline mutations in predisposing genes allows for risk ass...

    Snigdha Majumder, Rakshit Shah, Jisha Elias, Malini Manoharan… in Scientific Reports (2018)

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