Skip to main content

7 Result(s)

within Amer Ali Abd El-Hafeez Remove this filter

and

  1. No Access

    Article

    Anti-cancer Effect of Hyoscyamus muticus Extract via Its Activation of Fas/FasL-ASK1-p38 Pathway

    Hyoscyamus muticus L. is a traditional medicine used as antispasmodic and sedative. Herein, we aimed to determine the phytochemical constituents and for the first time its anti-cancer activities. The phytochemica...

    Amer Ali Abd El-Hafeez, Hala Mohamed M. Marzouk… in Biotechnology and Bioprocess Engineering (2022)

  2. No Access

    Article

    Grapefruit juice exerts anti-osteoporotic activities in a prednisolone-induced osteoporosis rat femoral fracture model, possibly via the RANKL/OPG axis

    This study aimed to shed light on the protective and therapeutic anti-osteoporotic effects and mechanisms of action of grapefruit juice (GFJ) on prednisolone-induced osteoporosis a rat femoral fracture model. ...

    Eslam Muhammad Bastawy, Rasha Rashad Ahmed, Amer Ali Abd El-Hafeez… in Cytotechnology (2019)

  3. No Access

    Article

    Anticancer effect of nor-wogonin (5, 7, 8-trihydroxyflavone) on human triple-negative breast cancer cells via downregulation of TAK1, NF-κB, and STAT3

    Nor-wogonin, a polyhydroxy flavone, has been shown to possess antitumor activity. However, the mechanisms responsible for its antitumor activity are poorly studied. Herein, we investigated the mechanisms of no...

    Amer Ali Abd El-Hafeez, Hazim O. Khalifa, Elham A. M. Mahdy… in Pharmacological Reports (2019)

  4. No Access

    Article

    Synergistic tumor suppression by a Perilla frutescens-derived methoxyflavanone and anti-cancer tyrosine kinase inhibitors in A549 human lung adenocarcinoma

    Anti-cancer tyrosine kinase inhibitors (TKIs) are effective in many types of cancers including non-small cell lung cancer, while appearance of TKI-resistant tumors suggests a need for the development of their ...

    Amer Ali Abd El-Hafeez, Takashi Fujimura, Rikiya Kamei, Noriko Hirakawa… in Cytotechnology (2018)

  5. No Access

    Article

    A methoxyflavanone derivative from the Asian medicinal herb (Perilla frutescens) induces p53-mediated G2/M cell cycle arrest and apoptosis in A549 human lung adenocarcinoma

    Perilla frutescens is an Asian dietary herb consumed as an essential seasoning in Japanese cuisine as well as used for a Chinese medicine. Here, we report that a newly found methoxyflavanone deri...

    Amer Ali Abd El-Hafeez, Takashi Fujimura, Rikiya Kamei, Noriko Hirakawa… in Cytotechnology (2018)

  6. No Access

    Article

    TERT enhances the survival rate of human fibroblasts under endoplasmic reticulum, Golgi apparatus, and lysosomal stresses

    The exposure of organelles, such as the endoplasmic reticulum (ER), Golgi apparatus (GA), and lysosomes, to stress activates death mechanisms. Recently, telomerase reverse transcriptase (TERT) has been shown t...

    Amer Ali Abd El-Hafeez, Toru Hosoi, Kanako Nakatsu, Mina Thon… in Biotechnology Letters (2018)

  7. No Access

    Article

    Melilotus indicus extract induces apoptosis in hepatocellular carcinoma cells via a mechanism involving mitochondria-mediated pathways

    Melilotus indicus, is a traditional medicine used as analgesic and emollient. Although Melilotus indicus extract (MIE) has recently been shown to suppress growth of several tumor cell lines, information regarding...

    Amer Ali Abd El-Hafeez, Hazim O. Khalifa, Rania Abdelrahman Elgawish… in Cytotechnology (2018)