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    Article

    EDD, the human orthologue of the hyperplastic discs tumour suppressor gene, is amplified and overexpressed in cancer

    EDD (E3 isolated by differential display), located at chromosome 8q22.3, is the human orthologue of the Drosophila melanogaster tumour suppressor gene ‘hyperplastic discs’ and encodes a HECT domain E3 ubiquitin p...

    Jennifer L Clancy, Michelle J Henderson, Amanda J Russell, David W Anderson… in Oncogene (2003)

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    Article

    Identification of a human HECT family protein with homology to the Drosophila tumor suppressor gene hyperplastic discs

    Use of the differential display technique to isolate progestin-regulated genes in T-47D human breast cancer cells led to identification of a novel gene, EDD. The cDNA sequence contains a 2799 amino acid open r...

    Michelle J Callaghan, Amanda J Russell, Erica Woollatt, Grant R Sutherland… in Oncogene (1998)