6 Result(s)
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Alyson A. Miller
English
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Article
Open AccessCigarette smoke extract exacerbates hyperpermeability of cerebral endothelial cells after oxygen glucose deprivation and reoxygenation
Cigarette smoking is a risk factor for stroke and is linked to stroke severity. Previous studies have shown that cigarette smoke extract (CSE) triggers endothelial dysfunction in vitro by initiating oxidative str...
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Article
Open AccessIschaemic stroke in mice induces lung inflammation but not acute lung injury
Stroke is a major cause of death worldwide and ischemic stroke is the most common subtype accounting for approximately 80% of all cases. Pulmonary complications occur in the first few days to weeks following i...
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Article
Open AccessEarly life overfeeding impairs spatial memory performance by reducing microglial sensitivity to learning
Obesity can lead to cognitive dysfunction including poor performance in memory tasks. However, poor memory is not seen in all obese humans and takes several months to develop in animal models, indicating the a...
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Reference Work Entry In depth
Reactive Oxygen Species and Cerebrovascular Diseases
In the normal physiologic state, reactive oxygen species (ROS) generation is intentional and important for the functioning of cerebral and systemic circulations. Furthermore, emerging evidence indicates that c...
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Article
Hydrogen sulfide protects endothelial nitric oxide function under conditions of acute oxidative stress in vitro.
The aim of this study was to examine the ability of H2S, released from NaHS to protect vascular endothelial function under conditions of acute oxidative stress by scavenging superoxide anions (O2
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Article
Vascular cognitive impairment and Alzheimer’s disease: role of cerebral hypoperfusion and oxidative stress
Cerebrovascular disease may lead to a wide range of cognitive changes, referred to collectively as vascular cognitive impairment. Stroke increases the risk of cognitive impairment and dementia, and may contrib...
