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  1. Article

    Open Access

    Treatments for Chronic Kidney Disease: A Systematic Literature Review of Randomized Controlled Trials

    Delaying disease progression and reducing the risk of mortality are key goals in the treatment of chronic kidney disease (CKD). New drug classes to augment renin–angiotensin–aldosterone system (RAAS) inhibitor...

    Juan Jose Garcia Sanchez, Juliette Thompson, David A. Scott in Advances in Therapy (2022)

  2. Article

    Open Access

    Vertebral fracture as a risk factor for self-harm: a retrospective cohort study

    The prevention of self-harm is an international public health priority. It is vital to identify at-risk populations, particularly as self-harm is a risk factor for suicide. This study aims to examine the risk ...

    James A. Prior, Fay Crawford-Manning, Rebecca Whittle in BMC Musculoskeletal Disorders (2021)

  3. Article

    Open Access

    Antibiotic use and the risk of rheumatoid arthritis: a population-based case-control study

    Antibiotic-induced disturbances of the human microbiota have been implicated in the development of chronic autoimmune conditions. This study aimed to assess whether antibiotic use is associated with the onset ...

    Alyshah Abdul Sultan, Christian Mallen, Sara Muller, Samantha Hider in BMC Medicine (2019)

  4. Article

    Open Access

    Comorbidities in polymyalgia rheumatica: a systematic review

    Comorbidities are known to exist in many rheumatological conditions. Polymyalgia rheumatica (PMR) is a common inflammatory rheumatological condition affecting older people which, prior to effective treatment, ...

    Richard Partington, Toby Helliwell, Sara Muller in Arthritis Research & Therapy (2018)

  5. Article

    Open Access

    Risk of chronic kidney disease in patients with gout and the impact of urate lowering therapy: a population-based cohort study

    An association between gout and renal disease is well-recognised but few studies have examined whether gout is a risk factor for subsequent chronic kidney disease (CKD). Additionally, the impact of urate-lower...

    Matthew Roughley, Alyshah Abdul Sultan, Lorna Clarson in Arthritis Research & Therapy (2018)

  6. Article

    Open Access

    Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study

    Glucocorticoids are associated with increased fracture risk and are the mainstay of treatment in polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). However, fracture risk in these conditions has not ...

    Zoe Paskins, Rebecca Whittle, Alyshah Abdul Sultan, Sara Muller in BMC Medicine (2018)

  7. Article

    Open Access

    Gout and subsequent erectile dysfunction: a population-based cohort study from England

    An association has been suggested between gout and erectile dysfunction (ED), however studies quantifying the risk of ED amongst gout patients are lacking. We aimed to precisely determine the population-level ...

    Alyshah Abdul Sultan, Christian Mallen, Richard Hayward in Arthritis Research & Therapy (2017)