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  1. Article

    Open Access

    Genome-wide microRNA profiling of human temporal lobe epilepsy identifies modulators of the immune response

    Mesial temporal lobe epilepsy (mTLE) is a chronic neurological disorder characterized by recurrent seizures. The pathogenic mechanisms underlying mTLE may involve defects in the post-transcriptional regulation...

    Anne A. Kan, Susan van Erp, Alwin A. H. A. Derijck… in Cellular and Molecular Life Sciences (2012)

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    Article

    Chromosome-wide nucleosome replacement and H3.3 incorporation during mammalian meiotic sex chromosome inactivation

    In mammalian males, the first meiotic prophase is characterized by formation of a separate chromatin domain called the sex body1. In this domain, the X and Y chromosomes are partially synapsed and transcriptional...

    Godfried W van der Heijden, Alwin A H A Derijck, Eszter Pósfai… in Nature Genetics (2007)