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  1. Article

    Open Access

    Aortic disease in Marfan syndrome is caused by overactivation of sGC-PRKG signaling by NO

    Thoracic aortic aneurysm, as occurs in Marfan syndrome, is generally asymptomatic until dissection or rupture, requiring surgical intervention as the only available treatment. Here, we show that nitric oxide (...

    Andrea de la Fuente-Alonso, Marta Toral, Alvaro Alfayate in Nature Communications (2021)