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  1. No Access

    Reference Work Entry In depth

    Biopsy of the Sentinel Lymph Node

    Lymphatic map** and sentinel lymph node biopsy are standard components of the care of newly diagnosed patients with clinically localized intermediate- and high-risk melanoma. The procedures are the culminati...

    Mark B. Faries, Alistair J. Cochran, Michael McLemore in Cutaneous Melanoma (2020)

  2. No Access

    Reference Work Entry In depth

    Classification and Histopathology of Melanoma

    While a melanoma may be suspected clinically, a definitive diagnosis usually requires pathologic assessment of a tissue biopsy. Pathologic diagnosis of melanoma requires evaluation of changes in the architectu...

    Richard A. Scolyer, Victor G. Prieto, David E. Elder in Cutaneous Melanoma (2020)

  3. No Access

    Living Reference Work Entry In depth

    Classification and Histopathology of Melanoma

    While a melanoma may be suspected clinically, a definitive diagnosis usually requires pathologic assessment of a tissue biopsy. Pathologic diagnosis of melanoma requires evaluation of changes in the architectu...

    Richard A. Scolyer, Victor G. Prieto, David E. Elder in Cutaneous Melanoma

  4. No Access

    Living Reference Work Entry In depth

    Biopsy of the Sentinel Lymph Node

    Lymphatic map** and sentinel lymph node biopsy are standard components of the care of newly diagnosed patients with clinically localized intermediate- and high-risk melanoma. The procedures are the culminati...

    Mark B. Faries, Alistair J. Cochran, Michael McLemore in Cutaneous Melanoma

  5. No Access

    Article

    High response rate to PD-1 blockade in desmoplastic melanomas

    Immune checkpoint blockade with anti-PD-1 or anti-PD-L1 agents produces a high response rate in patients with desmoplastic melanoma.

    Zeynep Eroglu, Jesse M. Zaretsky, Siwen Hu-Lieskovan, Dae Won Kim, Alain Algazi in Nature (2018)

  6. Article

    Open Access

    Cutaneous wound healing through paradoxical MAPK activation by BRAF inhibitors

    BRAF inhibitors are highly effective therapies for the treatment of BRAFV600-mutated melanoma, with the main toxicity being a variety of hyperproliferative skin conditions due to paradoxical activation of the mit...

    Helena Escuin-Ordinas, Shuoran Li, Michael W. **e, Lu Sun in Nature Communications (2016)

  7. Article

    Open Access

    Molecular enhancement of sentinel node evaluation

    Alistair J Cochran in Journal of Translational Medicine (2015)

  8. Article

    MSLT-I—response of clinical trial investigators

    Mark B. Faries, Alistair J. Cochran, John F. Thompson in Nature Reviews Clinical Oncology (2014)

  9. No Access

    Article

    Pilot Study on “Pericytic Mimicry” and Potential Embryonic/Stem Cell Properties of Angiotropic Melanoma Cells Interacting with the Abluminal Vascular Surface

    The interaction of tumor cells with the tumor vasculature is mainly studied for its role in tumor angiogenesis and intravascular metastasis of circulating tumor cells. In addition, a specific interaction of tu...

    Claire Lugassy, Madhuri Wadehra, **nmin Li, Mirko Corselli in Cancer Microenvironment (2013)

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    Article

    Reply to Letter to the Editor “Lymphoedema in the Observation and Biopsy Arms of MSLT-1” by Thomas, J Meirion (ASO-2011-04-0666)

    Mark B. Faries, Donald L. Morton, Alistair J. Cochran in Annals of Surgical Oncology (2011)

  11. No Access

    Article

    EANM-EORTC general recommendations for sentinel node diagnostics in melanoma

    The accurate diagnosis of a sentinel node in melanoma includes a sequence of procedures from different medical specialities (nuclear medicine, surgery, oncology, and pathology). The items covered are presented...

    Annette H. Chakera, Birger Hesse in European Journal of Nuclear Medicine and M… (2009)

  12. No Access

    Chapter

    Dendritic Cells in Tumor-Draining Lymph Nodes

    Dendritic cells are neither the most obvious nor the most abundant cells in lymph nodes, but are certainly among the most immunologically influential, acting primarily as highly potent professional antigen-pre...

    Alistair J. Cochran, Rong-Rong Huang, Eijun Itakura in Dendritic Cells in Cancer (2009)

  13. Article

    Tumour-induced immune modulation of sentinel lymph nodes

    Alistair J. Cochran, Rong-Rong Huang, Jonathan Lee in Nature Reviews Immunology (2008)

  14. No Access

    Article

    The rationale for sentinel-node biopsy in primary melanoma

    The value of sentinel-node biopsy for the management of localized primary melanoma has been questioned. In this Viewpoint, the authors discuss the data that support the routine use of sentinel-node biopsy, and...

    Donald L Morton, Alistair J Cochran, John F Thompson in Nature Clinical Practice Oncology (2008)

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    Article

    Tumour–induced immune modulation of sentinel lymph nodes

  16. In most patients with melanoma who develop metastases, the regional lymph nodes are the first organs to be affected.

  17. ...
  18. Alistair J. Cochran, Rong-Rong Huang, Jonathan Lee in Nature Reviews Immunology (2006)

  19. Article

    Immune responses in the draining lymph nodes against cancer: Implications for immunotherapy

    Regional lymph nodes are the first site for melanoma metastases. The sentinel node (SN), on the direct lymphatic drainage pathway, which usually harbors first metastases, demonstrates significant suppression i...

    Suyu Shu, Alistair J. Cochran, Rong-Rong Huang in Cancer and Metastasis Reviews (2006)

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    Article

    Invited commentary on “Decorative sentinel lymph node – a new entity?” by Vandeweyer and Van De Casseye

    Alistair J. Cochran in European Journal of Plastic Surgery (2005)

  21. No Access

    Chapter

    Accurate Evaluation of Nodal Tissues for the Presence of Tumor is Central to the Sentinel Node Approach

    Alistair J. Cochran, Alice Roberts in Selective Sentinel Lymphadenectomy for Hum… (2005)

  22. No Access

    Chapter

    Study of Sentinel Lymph Nodes in the Staging of Malignant Neoplasms

    Surgeons have long appreciated the significance of lymph node metastases to cancer prognosis. As far back as the 6th century, Actus of Amida observed that “malignant phlegmons” develop in the armpits of advanc...

    Alice A. Roberts, Alistair J. Cochran in Cancer Diagnostics (2004)

  23. No Access

    Article

    The place of lymphatic map** and sentinel node biopsy in oncology

    The techniques of sentinel lymphatic map** (LM) and sentinel lymph node biopsy (SLNB) have become almost routine for the staging of clinically node-negative patients with high-risk cutaneous melanoma. The te...

    Alistair J. Cochran, Alice A. Roberts in International Journal of Clinical Oncology (2003)

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