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    Article

    Delivery of local anaesthetics by a self-assembled supramolecular system mimicking their interactions with a sodium channel

    Site-1 sodium channel blockers (S1SCBs) act as potent local anaesthetics, but they can cause severe systemic toxicity. Delivery systems can be used to reduce the toxicity, but the hydrophilicity of S1SCBs make...

    Tianjiao Ji, Yang Li, **aoran Deng, Alina Y. Rwei… in Nature Biomedical Engineering (2021)

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    Article

    Skin-interfaced biosensors for advanced wireless physiological monitoring in neonatal and pediatric intensive-care units

    Standard clinical care in neonatal and pediatric intensive-care units (NICUs and PICUs, respectively) involves continuous monitoring of vital signs with hard-wired devices that adhere to the skin and, in certa...

    Ha Uk Chung, Alina Y. Rwei, Aurélie Hourlier-Fargette, Shuai Xu… in Nature Medicine (2020)

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    Article

    Ultrasound-triggered local anaesthesia

    On-demand relief of local pain would allow patients to control the timing, intensity and duration of nerve blocks in a safe and non-invasive manner. Ultrasound would be a suitable trigger for such a system, as...

    Alina Y. Rwei, Juan L. Paris, Bruce Wang, Wei** Wang… in Nature Biomedical Engineering (2017)