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  1. Article

    Open Access

    IRF4 deficiency vulnerates B-cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity

    The processes leading from disturbed B-cell development to adult B-cell progenitor acute lymphoblastic leukemia (BCP-ALL) remain poorly understood. Here, we describe Irf4−/− mice as prone to develo** BCP-ALL wi...

    Dennis Das Gupta, Christoph Paul, Nadine Samel… in Cell Death & Differentiation (2022)

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