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  1. Article

    Open Access

    A randomised, active- and placebo-controlled, three-period crossover trial to investigate short-term effects of the dipeptidyl peptidase-4 inhibitor linagliptin on macro- and microvascular endothelial function in type 2 diabetes

    Studies of dipeptidyl peptidase (DPP)-4 inhibitors report heterogeneous effects on endothelial function in patients with type 2 diabetes (T2D). This study assessed the effects of the DPP-4 inhibitor linaglipti...

    Thomas Jax, Alin Stirban, Arne Terjung, Habib Esmaeili… in Cardiovascular Diabetology (2017)

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  2. No Access

    Article

    Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment

    NMDA receptors in pancreatic beta cells inhibit glucose-stimulated insulin secretion, and inhibiting these receptors with an over-the-counter medication improves diabetes in mouse models

    Jan Marquard, Silke Otter, Alena Welters, Alin Stirban, Annelie Fischer… in Nature Medicine (2015)

  3. Article

    Open Access

    NMDA receptor dependent anti-diabetic effects

    Jan Marquard, Silke Otter, Alena Welters… in Molecular and Cellular Pediatrics (2014)

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  4. No Access

    Article

    Microvascular Dysfunction in the Context of Diabetic Neuropathy

    Microvascular dysfunction in diabetes plays a crucial role in the development of diabetic complications. The skin, as one of the most accessible organs, serves as a model for the investigation of microvascular...

    Alin Stirban in Current Diabetes Reports (2014)

  5. No Access

    Article

    Die Bedeutung von AGEs und ROS bei Atherosklerose

    „Advanced glycation end products“ (AGEs) zählen zu den „Newcomern“ der metabolischen Forschung der letzten 2–3 Jahrzehnte. Auch als Maillard-Produkte bekannt, gehören sie seit längerem zum Alltag der Lebensmit...

    Alin Stirban in Herz (2010)