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    Article

    Pharmacogenetic and clinical predictors of voriconazole concentration in hematopoietic stem cell transplant recipients receiving CYP2C19-guided dosing

    CYP2C19-guided voriconazole dosing reduces pharmacokinetic variability, but many patients remain subtherapeutic. The aim of this study was to evaluate the effect of candidate genes and a novel CYP2C haplotype on ...

    Jai N. Patel, Myra Robinson, Sarah A. Morris in The Pharmacogenomics Journal (2023)

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    Article

    Altered expression of CSF3R splice variants impacts signal response and is associated with SRSF2 mutations

    Three annotated CSF3R mRNA splice variants have been described. CSF3R-V1 is the wild-type receptor, while CSF3R-V4 is a truncated form increased in some patients with AML. CSF3R-V3 mRNA was identified in placenta...

    Amanda Lance, Lawrence J. Druhan, C. Greer Vestal, Nury M. Steuerwald in Leukemia (2020)

  3. Article

    GSK3β inhibition and LEF1 upregulation in skeletal muscle following a bout of downhill running

    Canonical Wnt signaling is important in skeletal muscle repair but has not been well characterized in response to physiological stimuli. The objective of this study was to assess the effect of downhill running...

    Hiral Amin, Judy Vachris, Alicia Hamilton in The Journal of Physiological Sciences (2014)