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Article
Military service and risk of subsequent drug use disorders among Swedish men
Environmental factors contribute substantially to risk for drug use disorders (DUD). The current study applies multiple methods to empirically test whether military service is associated with subsequent DUD, a...
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Article
Open AccessShared genetic liability for alcohol consumption, alcohol problems, and suicide attempt: Evaluating the role of impulsivity
Heavy drinking and diagnosis with alcohol use disorder (AUD) are consistently associated with risk for suicide attempt (SA). Though the shared genetic architecture among alcohol consumption and problems (ACP) ...
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Article
Clinical, environmental, and genetic risk factors for substance use disorders: characterizing combined effects across multiple cohorts
Substance use disorders (SUDs) incur serious social and personal costs. The risk for SUDs is complex, with risk factors ranging from social conditions to individual genetic variation. We examined whether model...
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Article
Open AccessCoffee and energy drink use patterns in college freshmen: associations with adverse health behaviors and risk factors
Public health concern over college students mixing caffeine-containing energy drinks (EDs) and alcohol has contributed to an array of ED-focused research studies. One review found consistent associations betwe...
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Article
Open AccessSocioeconomic correlates of incident and fatal opioid overdose among Swedish people with opioid use disorder
Opioid overdose (OD) and opioid OD death are major health threats to people with opioid use disorder (OUD). Socioeconomic factors are underexplored potential determinants of opioid OD. In this study, we assess...
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Article
Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders
Liability to alcohol dependence (AD) is heritable, but little is known about its complex polygenic architecture or its genetic relationship with other disorders. To discover loci associated with AD and charact...
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Article
Drinking to Cope: a Latent Class Analysis of Co** Motives for Alcohol Use in a Large Cohort of Adolescents
Alcohol consumption during adolescence is widespread, although there is considerable variation in patterns of use. The aim of this study was to identify patterns of co**-motivated alcohol use in a UK birth c...
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Article
Open AccessThe association between depressive symptoms from early to late adolescence and later use and harmful use of alcohol
Depressive symptoms and alcohol misuse contribute substantially to the global health burden. These phenotypes often manifest, and frequently co-occur, during adolescence. However, few studies have examined whe...
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Article
Pubertal Development Moderates the Importance of Environmental Influences on Depressive Symptoms in Adolescent Girls and Boys
Prevalence differences in depressive symptoms between the sexes typically emerge in adolescence, with symptoms more prevalent among girls. Some evidence suggests that variation in onset and progression of pube...
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Article
Depressive Symptoms and Alcohol Use are Genetically and Environmentally Correlated Across Adolescence
Depressive symptoms and alcohol use are frequently positively associated during adolescence. This study aimed to assess the heritability of each phenotype across adolescence; to assess potential shared liabili...
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Article
Open AccessA transcriptional network associated with natural variation in Drosophilaaggressive behavior
Aggressive behavior is an important component of fitness in most animals. Aggressive behavior is genetically complex, with natural variation attributable to multiple segregating loci with allelic effects that ...
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Article
Open AccessMutations in many genes affect aggressive behavior in Drosophila melanogaster
Aggressive behavior in animals is important for survival and reproduction. Identifying the underlying genes and environmental contexts that affect aggressive behavior is important for understanding the evoluti...
