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  1. Article

    Open Access

    Modelling respiratory syncytial virus age-specific risk of hospitalisation in term and preterm infants

    Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory infections in children worldwide. The highest incidence of severe disease is in the first 6 months of life, with infants bo...

    Fiona Giannini, Alexandra B. Hogan, Mohinder Sarna in BMC Infectious Diseases (2024)

  2. Article

    Open Access

    Modelling the impact of hybrid immunity on future COVID-19 epidemic waves

    Since the emergence of SARS-CoV-2 (COVID-19), there have been multiple waves of infection and multiple rounds of vaccination rollouts. Both prior infection and vaccination can prevent future infection and redu...

    Thao P. Le, Isobel Abell, Eamon Conway, Patricia T. Campbell in BMC Infectious Diseases (2024)

  3. Article

    Open Access

    Author Correction: Develo** a prediction model to estimate the true burden of respiratory syncytial virus (RSV) in hospitalised children in Western Australia

    Amanuel Tesfay Gebremedhin, Alexandra B. Hogan, Christopher C. Blyth in Scientific Reports (2024)

  4. Article

    Open Access

    Estimating long-term vaccine effectiveness against SARS-CoV-2 variants: a model-based approach

    With the ongoing evolution of the SARS-CoV-2 virus updated vaccines may be needed. We fitted a model linking immunity levels and protection to vaccine effectiveness data from England for three vaccines (Oxford...

    Alexandra B. Hogan, Patrick Doohan, Sean L. Wu in Nature Communications (2023)

  5. Article

    Optimizing social and economic activity while containing SARS-CoV-2 transmission using DAEDALUS

    To study the trade-off between economic, social and health outcomes in the management of a pandemic, DAEDALUS integrates a dynamic epidemiological model of SARS-CoV-2 transmission with a multi-sector economic ...

    David J. Haw, Giovanni Forchini, Patrick Doohan in Nature Computational Science (2022)

  6. Article

    Open Access

    Modelling the impact of vaccine hesitancy in prolonging the need for Non-Pharmaceutical Interventions to control the COVID-19 pandemic

    Vaccine hesitancy – a delay in acceptance or refusal of vaccines despite availability – has the potential to threaten the successful roll-out of SARS-CoV-2 vaccines globally. In this study, we aim to understan...

    Daniela Olivera Mesa, Alexandra B. Hogan, Oliver J. Watson in Communications Medicine (2022)

  7. Article

    Open Access

    Develo** a prediction model to estimate the true burden of respiratory syncytial virus (RSV) in hospitalised children in Western Australia

    Respiratory syncytial virus (RSV) is a leading cause of childhood morbidity, however there is no systematic testing in children hospitalised with respiratory symptoms. Therefore, current RSV incidence likely u...

    Amanuel Tesfay Gebremedhin, Alexandra B. Hogan, Christopher C. Blyth in Scientific Reports (2022)

  8. Article

    Open Access

    Analysis of the potential for a malaria vaccine to reduce gaps in malaria intervention coverage

    The RTS,S/AS01 malaria vaccine is currently being evaluated in a cluster-randomized pilot implementation programme in three African countries. This study seeks to identify whether vaccination could reach addit...

    H. Juliette T. Unwin, Lazaro Mwandigha, Peter Winskill, Azra C. Ghani in Malaria Journal (2021)

  9. Article

    Open Access

    A Systematic Review of the Costs Relating to Non-pharmaceutical Interventions Against Infectious Disease Outbreaks

    Non-pharmaceutical interventions (NPIs) are the cornerstone of infectious disease outbreak response in the absence of effective pharmaceutical interventions. Outbreak strategies often involve combinations of N...

    Janetta E. Skarp, Laura E. Downey in Applied Health Economics and Health Policy (2021)

  10. Article

    Open Access

    Health inequities and clustering of fever, acute respiratory infection, diarrhoea and wasting in children under five in low- and middle-income countries: a Demographic and Health Surveys analysis

    Pneumonia, diarrhoea and malaria are responsible for over one third of all deaths in children under the age of 5 years in low and middle sociodemographic index countries; many of these deaths are also associat...

    Peter Winskill, Alexandra B. Hogan, Julie Thwing, Lazaro Mwandigha in BMC Medicine (2021)

  11. Article

    Open Access

    Modelling the household-level impact of a maternal respiratory syncytial virus (RSV) vaccine in a high-income setting

    Respiratory syncytial virus (RSV) infects almost all children by the age of 2 years, with the risk of hospitalisation highest in the first 6 months of life. Development and licensure of a vaccine to prevent se...

    Patricia T. Campbell, Nicholas Geard, Alexandra B. Hogan in BMC Medicine (2020)

  12. Article

    The potential public health consequences of COVID-19 on malaria in Africa

    The burden of malaria is heavily concentrated in sub-Saharan Africa (SSA) where cases and deaths associated with COVID-19 are rising1. In response, countries are implementing societal measures aimed at curtailing...

    Ellie Sherrard-Smith, Alexandra B. Hogan, Arran Hamlet, Oliver J. Watson in Nature Medicine (2020)

  13. Article

    Open Access

    Modelling population-level impact to inform target product profiles for childhood malaria vaccines

    The RTS,S/AS01 vaccine for Plasmodium falciparum malaria demonstrated moderate efficacy in 5–17-month-old children in phase 3 trials, and from 2018, the vaccine will be evaluated through a large-scale pilot imple...

    Alexandra B. Hogan, Peter Winskill, Robert Verity, Jamie T. Griffin in BMC Medicine (2018)

  14. No Access

    Article

    A Model for the Spread of an Invasive Weed, Tradescantia fluminensis

    Tradescantia fluminensis is an invasive weed and a serious threat to native forests in eastern Australia and New Zealand. Current methods of eradication are often ineffective, so understa...

    Alexandra B. Hogan, Mary R. Myerscough in Bulletin of Mathematical Biology (2017)

  15. Chapter and Conference Paper

    Erratum to: Age Structures in Mathematical Models for Infectious Diseases, with a Case Study of Respiratory Syncytial Virus

    Alexandra B. Hogan, Kathryn Glass in Applications + Practical Conceptualization… (2016)

  16. No Access

    Chapter and Conference Paper

    Age Structures in Mathematical Models for Infectious Diseases, with a Case Study of Respiratory Syncytial Virus

    Mathematical modelling plays an important role in understanding the dynamics of transmissible infections, as information about the drivers of infectious disease outbreaks can help inform health care planning a...

    Alexandra B. Hogan, Kathryn Glass in Applications + Practical Conceptualization… (2016)

  17. No Access

    Chapter and Conference Paper

    The Formation and Launch of the Asia Pacific Consortium of Mathematics for Industry (APCMfI)

    The Forum “Math-for-Industry” 2014 (FMfI 2014) represented the first opportunity to formally showcase the concept and formation of the Asia Pacific Consortium of Mathematics for Industry (APCMfI). This new ini...

    Masato Wakayama, Alexandra B. Hogan in Applications + Practical Conceptualization… (2016)