3 Result(s)
within
Alexander Widiapradja
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Article
Open AccessRegulation of Cardiac Mast Cell Maturation and Function by the Neurokinin-1 Receptor in the Fibrotic Heart
Cardiac fibrosis is an underlying cause of diastolic dysfunction, contributing to heart failure. Substance P (SP) activation of the neurokinin-1 receptor (NK-1R) contributes to cardiac fibrosis in hypertension...
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Article
The role of neuropeptides in adverse myocardial remodeling and heart failure
In addition to traditional neurotransmitters of the sympathetic and parasympathetic nervous systems, the heart also contains numerous neuropeptides. These neuropeptides not only modulate the effects of neurotr...
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Article
Open AccessIntravenous immunoglobulin (IVIg) provides protection against endothelial cell dysfunction and death in ischemic stroke
The brain endothelium is a key component of the blood brain barrier which is compromised following ischemia, allowing infiltration of damaging immune cells and other inflammatory molecules into the brain. Intr...
