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Article
The nuclear translocation of ERK1/2 as an anticancer target
A hallmark of the ERK1/2 functioning is their nuclear translocation, which is mainly required for the induction of proliferation. Activated ERK1/2 molecules that remain in the cytoplasm initiate other activiti...
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Article
Open AccessHigh content image analysis reveals function of miR-124 upstream of Vimentin in regulating motor neuron mitochondria
microRNAs (miRNAs) are critical for neuronal function and their dysregulation is repeatedly observed in neurodegenerative diseases. Here, we implemented high content image analysis for investigating the impact...
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Article
Open AccessPRMT1 inhibition induces differentiation of colon cancer cells
Differentiation therapy has been recently revisited as a prospective approach in cancer therapy by targeting the aberrant growth, and repairing the differentiation and cell death programs of cancer cells. Howe...