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  1. Article

    Open Access

    APR-246 as a radiosensitization strategy for mutant p53 cancers treated with alpha-particles-based radiotherapy

    Radiation therapy (RT) remains a common treatment for cancer patients worldwide, despite the development of targeted biological compounds and immunotherapeutic drugs. The challenge in RT lies in delivering a l...

    Or Michaeli, Ishai Luz, Maayan Vatarescu, Tal Manko, Noam Weizman… in Cell Death & Disease (2024)

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  2. Article

    Open Access

    PICOT binding to chromatin-associated EED negatively regulates cyclin D2 expression by increasing H3K27me3 at the CCND2 gene promoter

    Protein kinase C (PKC)-interacting cousin of thioredoxin (PICOT; also termed glutaredoxin 3 (Grx3; Glrx3)) is a ubiquitous protein that can interact with the embryonic ectoderm development (EED) protein via ea...

    Pinakin Pandya, Minesh Jethva, Eitan Rubin, Ramon Y. Birnbaum… in Cell Death & Disease (2019)

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