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Article
Hinge craniotomy versus standard decompressive hemicraniectomy: an experimental preclinical comparative study
Decompressive craniectomy (DC) is the most common surgical procedure to manage increased intracranial pressure (ICP). Hinge craniotomy (HC), which consists of fixing the bone operculum with a pivot, is an alte...
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Article
Open AccessEfficacy and safety of flexible versus rigid endoscopic third ventriculostomy in pediatric and adult populations: a systematic review and meta-analysis
Endoscopic third ventriculostomy (ETV) is a well-established surgical procedure for hydrocephalus treatment, but there is sparse evidence on the optimal choice between flexible and rigid approaches. A meta-ana...
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Chapter
Hemorrhagic Stroke: Endoscopic Aspiration
Intracerebral hemorrhage (ICH) and intraventricular hemorrhage (IVH) carry a very dismal prognosis. Several medical and surgical attempts have been made to reduce mortality and to improve neurological outcomes...
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Article
Open AccessAneurismal subarachnoid hemorrhage during the COVID-19 outbreak in a Hub and Spoke system: observational multicenter cohort study in Lombardy, Italy
Lombardy was the most affected Italian region by the first phase of the COVID-19 pandemic and underwent urgent reorganization for the management of emergencies, including subarachnoid hemorrhage from a rupture...
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Article
Open AccessHow I do it: flexible endoscopic aspiration of intraventricular hemorrhage
As intraventricular blood is a strong negative prognostic factor, intraventricular hemorrhage requires prompt and aggressive management to reduce intracranial hypertension.
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Article
New perspectives in the endoscopic treatment of brain purulent collections: targets, techniques, results in a case series, and overview of the literature
Purulent intracranial infections are threatening conditions. Different surgical approaches have been described, respecting the rationale of evacuating the fluid component of the purulent collection. Emerging e...
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Protocol
Surgical Management of Brain Cavernous Malformations
Surgical removal of accessible lesions is the only direct therapeutic approach for cerebral cavernous malformations (CCMs). The approach should be carefully evaluated according to clinical, anatomical, and neu...
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Reference Work Entry In depth
Cerebrospinal Fluid Circulation
The classic model of cerebrospinal fluid (CSF) formation, transport across the central nervous system, and absorption is based on the circulation theory. This model, where CSF is thought to be secreted by the ...
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Living Reference Work Entry In depth
Cerebrospinal Fluid Circulation
The classic model of cerebrospinal fluid (CSF) formation, transport across the central nervous system, and absorption is based on the circulation theory. This model, where CSF is thought to be secreted by the ...
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Article
Aspiration of parafalcine empyemas with flexible scope
Subdural empyemas are considered neurosurgical emergencies, and the parafalcine location is particularly insidious. We revised the experience of general surgeons who are used to manage chronic pleural purulent...
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Article
Split cerebral aqueduct: a neuroendoscopic illustration
Forking of the cerebral aqueduct is a developmental malformation that is infrequently encountered by neurosurgeons as a rare cause of hydrocephalus, sometimes with a delayed onset. The etiology of an apparentl...
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Article
Third ventriculostomy site as a neuroreceptorial area
Endoscopic third ventriculostomy is an established method for treating hydrocephalus. The third ventriculostomy site is considered a safe area that can be disrupted during surgical endoscopic procedures. The q...
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Article
Neuroendoscopic aspiration of tumors in the posterior third ventricle and aqueduct lumen: a technical update
Small soft ventricular tumors are good candidates for complete removal by a purely endoscopic technique. This approach is particularly interesting for lesions located in the posterior third ventricle and aqued...
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Article
A restricted neuroendoscopic approach for pathological diagnosis of intraventricular and paraventricular tumours
There is increasing interest in the use of neuroendoscopic techniques in neuro-oncology. We report our experience of endoscopic biopsy in patients harbouring intraventricular and paraventricular brain tumours ...
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Article
Lactacystin Exhibits Potent Anti-tumor Activity in an Animal Model of Malignant Glioma when Administered via Controlled-release Polymers
Lactacystin, a proteasome-inhibitor, has been shown to induce apoptosis of experimental gliomas in vitro. However, its systemic toxicity prevents further clinical use. To circumvent this problem, lactacystin can ...