29 Result(s)
within
Alessandro Di Martino
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Article
Open AccessThe reimbursement system can influence the treatment choice and favor joint replacement versus other less invasive solutions in patients affected by osteoarthritis
The aim of this study was to assess how physicians perceive the role of the reimbursement system and its potential influence in affecting their treatment choice in the management of patients affected by osteoa...
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Article
Combined subchondral and intra-articular injections of bone marrow aspirate concentrate provide stable results up to 24 months
The aim of this study was to evaluate the clinical and imaging findings up to 24 months of follow-up in patients treated with combined subchondral and intra-articular bone marrow aspirate concentrate (BMAC) in...
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Article
Chitosan based scaffold applied in patellar cartilage lesions showed positive clinical and MRI results at minimum 2 years of follow up
New scaffold-based cartilage regeneration techniques have been developed to improve the results of microfractures also in complex locations like the patello-femoral joint. The aim of this study was to analyse ...
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Article
Bone marrow aspirate concentrate injections provide similar results versus viscosupplementation up to 24 months of follow-up in patients with symptomatic knee osteoarthritis. A randomized controlled trial
The purpose of this double-blind randomized controlled trial (RCT) was to compare clinical improvement and radiographic findings up to 2 years of follow-up of a single intra-articular injection of bone marrow ...
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Article
The 50 most-cited clinical articles in cartilage surgery research: a bibliometric analysis
Articular cartilage lesions remain a challenge for orthopedic surgeons. The identification of the most important articles can help identifying the most influential techniques of the past, the current prevalent...
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Article
Open AccessUnion, complication, reintervention and failure rates of surgical techniques for large diaphyseal defects: a systematic review and meta-analysis
To understand the potential and limitations of the different available surgical techniques used to treat large, long-bone diaphyseal defects by focusing on union, complication, re-intervention, and failure rat...
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Chapter
Cartilage Lesions and Osteoarthritis of the Knee: Biologics
Conservative treatments currently used to address knee articular degenerative defects and osteoarthritis (OA), including physiotherapy, anti-inflammatory, and anti-pain medications, have modest and short-lasti...
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Article
Subchondral and intra-articular injections of bone marrow concentrate are a safe and effective treatment for knee osteoarthritis: a prospective, multi-center pilot study
Subchondral bone is becoming a treatment target for knee OA patients, with promising early findings on the use of bone marrow aspirate concentrate (BMAC). The aim of this prospective, multi-centric pilot study...
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Article
Open AccessMulti-layer cell-free scaffolds for osteochondral defects of the knee: a systematic review and meta-analysis of clinical evidence
The aim of this study was to analyze the clinical results provided by multi-layer cell-free scaffolds for the treatment of knee osteochondral defects.
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Article
Matrix-assisted chondrocyte transplantation with bone grafting for knee osteochondritis dissecans: stable results at 12 years
To document clinical and radiological results of arthroscopic matrix-assisted autologous chondrocyte transplantation (MACT) combined with bone grafting for the treatment of knee osteochondritis dissecans (OCD)...
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Article
Open AccessOsteochondral autograft transplantation versus autologous bone-cartilage paste grafting for the treatment of knee osteochondritis dissecans
To compare the results of two groups of patients affected by osteochondritis dissecans (OCD) of the knee and treated with either osteochondral autologous transplantation (OAT) or bone-cartilage paste grafting ...
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Article
Open AccessSmall Extracellular Vesicles from adipose derived stromal cells significantly attenuate in vitro the NF-κB dependent inflammatory/catabolic environment of osteoarthritis
The therapeutic ability of Mesenchymal Stem/Stromal Cells to address osteoarthritis (OA) is mainly related to the secretion of biologically active factors, which can be found within their secreted Extracellula...
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Chapter
The Illustrative Chondral and Osteochondral Scaffolds in Cartilage Repair
Articular chondral lesions are one of the most challenging conditions for the orthopaedic surgeon, representing a painful pathology which can evolve into osteoarthritis (OA). Several surgical techniques have b...
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Chapter and Conference Paper
Gaussian Process Deep Belief Networks: A Smooth Generative Model of Shape with Uncertainty Propagation
The shape of an object is an important characteristic for many vision problems such as segmentation, detection and tracking. Being independent of appearance, it is possible to generalize to a large range of ob...
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Article
Anterior cruciate ligament injury: post-traumatic bone marrow oedema correlates with long-term prognosis
Bone marrow oedema (BME) in the knee is a feature of several pathological conditions, and it has been described with high frequency in patients with acute anterior cruciate ligament (ACL) injury. The aim of th...
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Article
A one-step treatment for chondral and osteochondral knee defects: clinical results of a biomimetic scaffold implantation at 2 years of follow-up
The increasing interest in the role of subchondral bone with regard to articular surface disease led to the development of new bioengineered strategies. Aim of this study is to evaluate the clinical and MRI ou...
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Article
Is the clinical outcome after cartilage treatment affected by subchondral bone edema?
Subchondral bone edema is a common finding after cartilage treatment, but its interpretation is still debated. The aim of this study is to analyse the presence of edema after matrix-assisted autologous chondro...
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Article
Biodegradable polyurethane meniscal scaffold for isolated partial lesions or as combined procedure for knees with multiple comorbidities: clinical results at 2 years
The aim of this study is to evaluate the safety and clinical efficacy of this novel polyurethane meniscal scaffold to treat partial meniscal loss.
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Article
Platelet-rich plasma for the treatment of patellar tendinopathy: clinical and imaging findings at medium-term follow-up
The purpose of this study was to evaluate the efficacy of multiple platelet-rich plasma (PRP) injections on the healing of chronic refractory patellar tendinopathy, and report the quality and duration of the c...
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Article
Open AccessPlatelet-rich plasma vs hyaluronic acid to treat knee degenerative pathology: study design and preliminary results of a randomized controlled trial
Platelet Rich Plasma (PRP), a blood-derived product rich in growth factors, is a promising treatment for cartilage defects but there is still a lack of clinical evidence. The aim of this study is to show, thro...
