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  1. No Access

    Article

    Disseminated nocardiosis and anti-GM-CSF antibodies

    Infections that are unusually severe or caused by opportunistic pathogens are a hallmark of primary immunodeficiency (PID). Anti-cytokine autoantibodies (ACA) are an emerging cause of acquired immunodeficiency...

    Barbara Brugnoli, Lorenzo Salvati in European Journal of Clinical Microbiology … (2024)

  2. Article

    Open Access

    Scalp eschar and neck lymph adenopathy after a tick bite (SENLAT) in Tuscany, Italy (2015–2022)

    The Scalp Eschar and Neck Lymph Adenopathy After a Tick Bite (SENLAT) syndrome is frequently caused by Rickettsia slovaca and Rickettsia raoultii. Only six microbiologically confirmed SENLAT cases have been repor...

    Anna Barbiero, Tommaso Manciulli, Michele Spinicci, Iacopo Vellere in Infection (2023)

  3. Article

    Open Access

    Visceral larva Migrans in a Young Italian Patient: A Diagnostic Dilemma

    The association of fever, focal hepatic lesions and peripheral hyper-eosinophilia (FHLH) can be observed in both infectious and non-infectious conditions. Fascioliasis, capillariasis, toxocariasis, all causes ...

    Emanuela Francalanci, Tommaso Manciulli, Giulia Bandini in Acta Parasitologica (2023)

  4. Article

    Open Access

    Doubts and concerns about COVID-19 uncertainties on imaging data, clinical score, and outcomes

    COVID-19 is a pandemic disease affecting predominantly the respiratory apparatus with clinical manifestations ranging from asymptomatic to respiratory failure. Chest CT is a crucial tool in diagnosing and eval...

    Cosimo Nardi, Andrea Magnini, Linda Calistri, Edoardo Cavigli in BMC Pulmonary Medicine (2023)

  5. Article

    Open Access

    Schistosomiasis in non-endemic areas: Italian consensus recommendations for screening, diagnosis and management by the Italian Society of Tropical Medicine and Global Health (SIMET), endorsed by the Committee for the Study of Parasitology of the Italian Association of Clinical Microbiologists (CoSP-AMCLI), the Italian Society of Parasitology (SoIPa), the Italian Society of Gastroenterology and Digestive Endoscopy (SIGE), the Italian Society of Gynaecology and Obstetrics (SIGO), the Italian Society of Colposcopy and Cervico-Vaginal Pathology (SICPCV), the Italian Society of General Medicine and Primary Care (SIMG), the Italian Society of Infectious and Tropical Diseases (SIMIT), the Italian Society of Pediatrics (SIP), the Italian Society of Paediatric Infectious Diseases (SITIP), the Italian Society of Urology (SIU)

    Agnese Comelli, Camilla Genovese, Federico Gobbi, Gaetano Brindicci in Infection (2023)

  6. Article

    Open Access

    Diagnosis and management of complicated urogenital schistosomiasis: a systematic review of the literature

    Currently, there are no standardized guidelines for the diagnosis or management of the complications of urogenital schistosomiasis (UGS). This systematic review of the literature aims to investigate the state ...

    Tommaso Manciulli, Davide Marangoni, Joaquin Salas-Coronas, Cristina Bocanegra in Infection (2023)

  7. Article

    Open Access

    Tuberculosis in the European Region

    Tuberculosis (TB) remains a major public health concern worldwide. The COVID-19 pandemic and migration flow due to socioeconomic conditions, climate change, and geopolitical issues, such as the war, are import...

    Jessica Mencarini, Michele Spinicci, Lorenzo Zammarchi in Current Tropical Medicine Reports (2023)

  8. Article

    Open Access

    Characteristics of COVID-19 vaccinated and unvaccinated patients admitted to Careggi University Hospital, Florence, Italy

    More than 11.5 billion COVID-19 vaccine doses have been administered around the world. Although vaccine effectiveness for severe infections is reported to be 89.0%, breakthrough infections are common and may l...

    Riccardo Paggi, Anna Barbiero, Tommaso Manciulli in Internal and Emergency Medicine (2023)

  9. Article

    Open Access

    Long-term SARS-CoV-2 Asymptomatic Carriage in an Immunocompromised Host: Clinical, Immunological, and Virological Implications

    SARS-CoV-2 infection in immunocompromised hosts is challenging, and prolonged viral shedding can be a common complication in these patients. We describe the clinical, immunological, and virological course of a...

    Michele Spinicci, Alessio Mazzoni, Marco Coppi in Journal of Clinical Immunology (2022)

  10. Article

    Open Access

    Treatment with anti-SARS-CoV-2 monoclonal antibodies in pregnant and postpartum women: first experiences in Florence, Italy

    Pregnant and postpartum women are at increased risk of develo** severe COVID-19. Monoclonal antibodies (mAbs) are now widely used in high-income countries to treat mild to moderate COVID-19 outpatients at ri...

    Tommaso Manciulli, Giulia Modi, Irene Campolmi, Beatrice Borchi in Infection (2022)

  11. Article

    Open Access

    Clinical and Immunological Features of SARS-CoV-2 Breakthrough Infections in Vaccinated Individuals Requiring Hospitalization

    Waning immunity and the surge of SARS-CoV-2 variants are responsible for breakthrough infections, i.e., infections in fully vaccinated individuals. Although the majority of vaccinated infected subjects report ...

    Giulia Lamacchia, Alessio Mazzoni, Michele Spinicci in Journal of Clinical Immunology (2022)

  12. Article

    Open Access

    Artesunate monotherapy versus artesunate plus quinine combination therapy for treatment of imported severe malaria: a TropNet retrospective cohort study

    The addition of intravenous quinine (IVQ) to intravenous artesunate (IVA) has been recently suggested by World Health Organization  in areas where artemisinin resistance is highly prevalent. Since IVA is not y...

    Annarita Botta, Agnese Comelli, Iacopo Vellere, Flavia Chechi, Leila Bianchi in Infection (2022)

  13. Article

    Open Access

    Letter to the Editor Regarding Management of Adult Patients with COVID-19 Outside Intensive Care Units: Guidelines from the Italian Society of Anti-Infective Therapy (SITA) and the Italian Society of Pulmonology (SIP)

    Recently, the Italian Society of Anti-Infective Therapy (SITA) and the Italian Society of Pulmonology (SIP) published guidelines on the management of inpatients with COVID-19. The guidelines do not recommend t...

    Tommaso Manciulli, Michele Spinicci in Infectious Diseases and Therapy (2022)

  14. Article

    Strongyloidiasis in the COVID era: a warning for an implementation of the screening protocol

    Iacopo Vellere, Lucia Graziani, Marta Tilli, Antonia Mantella, Irene Campolmi in Infection (2021)

  15. No Access

    Article

    Ceftolozane/tazobactam for Pseudomonas aeruginosa pulmonary exacerbations in cystic fibrosis adult patients: a case series

    Management of cystic fibrosis (CF) patients colonized with Pseudomonas aeruginosa is challenging due to its virulence and multi-drug resistance. Ceftolozane/tazobactam (C/T) is a promising new antipseudomonal age...

    Letizia Ottino, Filippo Bartalesi in European Journal of Clinical Microbiology … (2021)

  16. Article

    Open Access

    Disseminated and Relapsing Cryptococcosis: What We Still Have to Learn—a Case Series and Review of Literature

    Two cases of disseminated cryptococcosis are described. The first was an HIV-infected patient where cryptococcosis was diagnosed as “unmasking immune reconstitution syndrome”; the second was an immunosuppresse...

    Annarita Botta, Matteo Piccica, Filippo Lagi in SN Comprehensive Clinical Medicine (2021)

  17. Article

    High-dose steroids for the treatment of severe COVID-19

    Matteo Piccica, Filippo Lagi, Michele Trotta in Internal and Emergency Medicine (2021)

  18. Article

    Open Access

    Compassionate use of JAK1/2 inhibitor ruxolitinib for severe COVID-19: a prospective observational study

    Overwhelming inflammatory reactions contribute to respiratory distress in patients with COVID-19. Ruxolitinib is a JAK1/JAK2 inhibitor with potent anti-inflammatory properties. We report on a prospective, obse...

    Alessandro M. Vannucchi, Benedetta Sordi, Alessandro Morettini, Carlo Nozzoli in Leukemia (2021)

  19. Article

    Open Access

    Toxoplasma gondii and multiple sclerosis: a population-based case–control study

    According to the hygiene hypothesis, parasites could have a protective role in the development of Multiple Sclerosis (MS). Our aim was to assess the association between presence of anti-Toxoplasma gondii antibodi...

    Alessandra Nicoletti, Calogero Edoardo Cicero, Loretta Giuliano in Scientific Reports (2020)

  20. No Access

    Article

    Chagas disease in Italy: updated estimates

    Irene Campolmi, Andrea Angheben, Filomena Bruna Aliani in Internal and Emergency Medicine (2020)

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