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  1. Article

    Open Access

    Rational optimization of a transcription factor activation domain inhibitor

    Transcription factors are among the most attractive therapeutic targets but are considered largely ‘undruggable’ in part due to the intrinsically disordered nature of their activation domains. Here we show tha...

    Shaon Basu, Paula Martínez-Cristóbal in Nature Structural & Molecular Biology (2023)