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  1. Article

    Open Access

    Socio-economic variation in CT scanning in Northern England, 1990-2002

    Socio-economic status is known to influence health throughout life. In childhood, studies have shown increased injury rates in more deprived settings. Socio-economic status may therefore be related to rates of...

    Mark S Pearce, Jane A Salotti, Kieran McHugh, Kwang Pyo Kim… in BMC Health Services Research (2012)

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    Article

    CT scans in young people in Northern England: trends and patterns 1993–2002

    Although CT can be greatly beneficial, its relatively high radiation doses have caused public health concerns.

    Mark S. Pearce, Jane A. Salotti, Kieran McHugh, Wenhua Metcalf… in Pediatric Radiology (2011)

  3. No Access

    Chapter

    Osteosarcoma: The European Osteosarcoma Intergroup (EOI) Perspective

    In the late 1970s, there was confusion regarding the best management for osteosarcoma. The benefit of chemotherapy had not been established and which chemotherapy could be used was even more uncertain. The Eur...

    Alan W. Craft in Pediatric and Adolescent Osteosarcoma (2010)

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    Article

    Prohibitive toxicity of a dose-intense regime for metastatic neuroblastoma containing ifosfamide, doxorubicin and cisplatin

    Three patients with stage 4 neuroblastoma were treated with a schedule comprising alternating modules of myelosuppressive (ifosfamide, etoposide, doxorubicin) and less myelosuppressive (vincristine, cisplatin)...

    Stephen P. Lowis, Andrew D. J. Pearson… in Cancer Chemotherapy and Pharmacology (1993)

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    Article

    Assessment of chemotherapy-associated nephrotoxicity in children with cancer

    Assessment of the toxicity caused by chemotherapy in children with cancer has become more important as the number of long-term survivors has continued to increase. It is vital to monitor both acute life-threat...

    Roderick Skinner, Andrew D. J. Pearson… in Cancer Chemotherapy and Pharmacology (1991)

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    Article

    Toxicity of high-dose ifosfamide in children

    Ifosfamide has been shown to be an active agent in the treatment of several childhood cancers. However, the optimal dose and method of administration remains to be established. The dose/response relationship o...

    Stella M. Davies, Andrew D. J. Pearson… in Cancer Chemotherapy and Pharmacology (1989)

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    Chapter

    Accidental injury and death in children

    Accidents are by far and away the commonest cause of death in childhood and are an equally important reason for the admission of children to hospital. Although accident rates have fallen slowly throughout this...

    Alan W. Craft in Paediatric Forensic Medicine and Pathology (1989)

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    Article

    Pharmacokinetics of oral and intramuscular methotrexate in children with acute lymphoblastic leukaemia

    Repeated methotrexate absorption studies were performed under standard conditions in 127 children receiving either oral or intramuscular methotrexate for acute lymphoblastic leukaemia. There was marked variabi...

    Andrew D. J. Pearson, Steven Mills… in Cancer Chemotherapy and Pharmacology (1987)