-
Book
-
Chapter
Human Cathepsin D
Our interest in cathepsin D arose from the observation that agents such as vitamin A alcohol and complement-sufficient antiserum, which caused a dramatic catabolism of cartilage matrix in a culture system, sim...
-
Chapter
The Neutral Proteinases of Human Spleen
Hedin (1) reported that bovine spleen preparations showed proteolytic activity in both acidic and alkaline conditions. Many years later, the acidic-acting peptide hydrolases of this tissue were the subject of ...
-
Article
Evolution of proteins of the cystatin superfamily
We have examined the amino acid sequences of a number of proteins that have been suggested to be related to chicken cystatin, a protein from chicken egg white that inhibits cysteine proteinases. On the basis o...
-
Chapter
Peptidases: a view of classification and nomenclature
It is beyond question that the results of research on proteolytic enzymes, or peptidases, are already benefiting mankind in many ways, and there is no doubt that research in this area has the potential to cont...
-
Article
Open AccessA comparison of Pfam and MEROPS: Two databases, one comprehensive, and one specialised.
We wished to compare two databases based on sequence similarity: one that aims to be comprehensive in its coverage of known sequences, and one that specialises in a relatively small subset of known sequences. ...