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Article
Long-term dynamic simulation of adipogenic differentiation of a human mesenchymal stem cell
Multibody dynamic simulations of the mechanobiology of cellular processes have not been obtained for time histories of orders larger than one second even with the employment of supercomputers. A mechanobiologi...
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Article
Elimination approach toward normalization constraint for Euler parameters
It is known that three-parameter representations of spatial rotation suffer from kinematic singularities. Euler parameters (unit quaternions) are a four-parameter solution for this issue. However, a normality ...
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Article
Estimation of impact forces during multi-point collisions involving small deformations
Collision between hard objects causes abrupt changes in the velocities of the system, which are characterized by very large contact forces over very small time durations. A common approach in the analysis of s...
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Living Reference Work Entry In depth
Macro-mini Manipulation
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Article
Open AccessCorrelation between Nuclear Morphology and Adipogenic Differentiation: Application of a Combined Experimental and Computational Modeling Approach
Stem cells undergo drastic morphological alterations during differentiation. While extensive studies have been performed to examine the cytoskeletal remodeling, there is a growing interest to determine the mor...
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Article
Modeling three-dimensional surface-to-surface rigid contact and impact
This work presents a rigid body framework for analyzing three-dimensional surface contacts and impacts as a simultaneous multi-point impact problem with friction. A method is developed to address the indetermi...
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Article
Analytic solution for planar indeterminate impact problems using an energy constraint
This work proposes an analytic method for resolving planar multi-point indeterminate impact problems for rigid-body systems. An event-based approach is used to detect impact events, and constraints consistent ...
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Article
A multiscale modeling approach for biomolecular systems
This paper presents a new multiscale molecular dynamic model for investigating the effects of external interactions, such as contact and impact, during step** and docking of motor proteins and other biomolec...
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Article
Study of Newton’s cradle using a new discrete approach
This paper presents a new discrete approach for treating simultaneous, multiple point, indeterminate impact. The proposed approach uses rigid body constraints to address the indeterminacy in the equations of moti...
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Article
Dynamic model of estrogen docking using multiscale analysis
This work investigates the application of a new multiscale analysis to dynamic modeling of the interaction between the estrogen molecule and its receptor. The key notion here is to explore the applications of ...
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Article
Dynamics of microscopic objects in optical tweezers: experimental determination of underdamped regime and numerical simulation using multiscale analysis
This article presents new experimental observations and numerical simulations to investigate the dynamic behavior of micro–nano-sized objects under the influence of optical tweezers (OTs). OTs are scientific t...
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Article
A new switching strategy for addressing Euler parameters in dynamic modeling and simulation of rigid multibody systems
This paper presents a new numerical strategy to address the extraneous coordinates in the Euler parameters. These parameters are unit quaternions with four variables, which have been used to describe the three...
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Article
Solution to indeterminate multipoint impact with frictional contact using constraints
This work presents a method for determining the post-impact behavior of a rigid body undergoing multiple, simultaneous impact with friction. A discrete algebraic model is used with an event-driven function whi...
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Article
Simultaneous oblique impacts and contacts in multibody systems with friction
This paper presents a new dissipation principle for resolving post-impact tangential velocities after simultaneous impact events on a system composed of interconnected rigid bodies. In this work, contact is co...
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Article
Energetically consistent simulation of simultaneous impacts and contacts in multibody systems with friction
This paper presents a methodology for treating energy consistency when considering simultaneous impacts and contacts with friction in the simulation of systems of interconnected bodies. Hard impact and contact...
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Chapter
Modular Decomposition for Optimal Dynamic Design of Redundant Macro/Mini Manipulators
This article investigates the design of redundant mechanisms for improved dynamic performance. Our study has resulted in a new methodology which allows the decomposition of the design problem into smaller, mor...
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Chapter
Optimization of the Inertial and Acceleration Characteristics of Non-Redundant Manipulators
This article investigates the problem of manipulator design for increased dynamic performance. Optimization techniques are used to determine the design parameters that improve manipulator performance. The dyna...
