-
Article
Rapid tumor progression complicated with liver abscess in a patient with gastric cancer receiving nivolumab therapy
Immune checkpoint inhibitors have been approved for treating various cancer types. However, several studies reported rapid tumor progression, a condition known as hyperprogressive disease, after treatment with...
-
Article
Open AccessEfficacy of tyrosine kinase inhibitors in patients with non-small-cell lung cancer with performance status 4: a case series and review of the literature
Current guidelines for non-small-cell lung cancer (NSCLC) recommend that each tyrosine kinase inhibitor (TKI) is indicated even for driver mutation-positive patients with a poor performance status (PS). In pre...
-
Article
Eldest gastric cancer patient with high microsatellite instability responding to pembrolizumab
Pembrolizumab has been associated with a high tumor response rate among high microsatellite instability (MSI-H) cancer patients. The efficacy and safety of pembrolizumab in the treatment of MSI-H gastric cance...
-
Article
Dabrafenib plus trametinib treatment for a patient with BRAF V600E-mutated large-cell lung carcinoma and a poor performance status
Dabrafenib plus trametinib is active against metastatic lung cancer with the BRAF V600E mutation. However, the feasibility of dabrafenib plus trametinib for patients with a poor performance status (PS) has not...
-
Article
Enhanced tumor response to radiotherapy after PD-1 blockade in metastatic gastric cancer
Immune checkpoint inhibitors may enhance the efficacy of radiotherapy (RT) in cancer treatment but the effect remains unknown in metastatic gastric cancer (mGC). This study aimed to compare the tumor shrinkage...
-
Article
Predictive factors for hyperprogressive disease during nivolumab as anti-PD1 treatment in patients with advanced gastric cancer
Hyperprogressive disease (HPD) during treatment with anti-programmed death-1/programmed death-ligand 1 monoclonal antibodies has anecdotally been reported in some types of cancers, but is not well-characterize...
-
Article
Open AccessClinicopathological and molecular features of responders to nivolumab for patients with advanced gastric cancer
Clinicopathological and molecular features of responders to nivolumab for advanced gastric cancer (AGC) are not well understood.
-
Article
Localized malignant mesothelioma in the middle mediastinum: Report of a case
Localized malignant mesothelioma in the mediastinum is rare and most known cases have been reported as “localized malignant pericardial mesothelioma.” We report a case of a middle mediastinal tumor, which we w...
-
Article
Internal hernia with triple hiatus of congenital origin: Report of a case
We report herein the case of a 65-year-old woman who was referred to our department with prolonged ileus symptoms despite conservative therapy. A plain abdominal radiograph showed intestinal gas shadows with a...
