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  1. Article

    Open Access

    Evaluating the effectiveness of combined T4 and T3 therapy or desiccated thyroid versus T4 monotherapy in hypothyroidism: a systematic review and meta-analysis

    Persistent symptoms in hypothyroid patients despite normalized TSH levels suggest the need for alternative treatments. This study aims to evaluate the effectiveness of combined T4 and T3 therapy or desiccated ...

    Mahmoud Nassar, Ahmed Hassan, Shrouk Ramadan… in BMC Endocrine Disorders (2024)

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  2. No Access

    Article

    Glycaemia and insulin after acute myocardial infarction

    The long-term outcomes of the DIGAMI 1 study indicate that intensive glucose lowering could be beneficial after an acute myocardial infarction in patients with type 2 diabetes mellitus. However, questions have...

    Paresh Dandona, Ajay Chaudhuri in Nature Reviews Endocrinology (2014)

  3. Article

    Open Access

    Macronutrient intake induces oxidative and inflammatory stress: potential relevance to atherosclerosis and insulin resistance

    With the global increase in the epidemic of obesity and type 2 diabetes with a concomitant increase in atherosclerotic disease, an investigation into the effects of various macronutrients and food products has...

    Paresh Dandona, Husam Ghanim, Ajay Chaudhuri… in Experimental & Molecular Medicine (2010)

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  4. No Access

    Chapter

    The Anti-Inflammatory and Antiatherogenic Effects of Insulin

    The concept that insulin affects carbohydrate, lipid, and protein metabolism and that its deficiency leads to diabetes mellitus has given this hormone a central position as a key metabolic regulator. However, ...

    Paresh Dandona, Ajay Chaudhuri, Husam Ghanim, Priya Mohanty in Cardiovascular Endocrinology (2009)

  5. No Access

    Article

    Use of Insulin to Improve Glycemic Control in Diabetes Mellitus

    The restoration of normoglycemia ensures the control of diabetic symptoms and reduction in microangiopathic complications in type 1 and type 2 diabetes. However, there is no conclusive evidence that intensive ...

    Paresh Dandona, Ajay Chaudhuri, Husam Ghanim… in Cardiovascular Drugs and Therapy (2008)

  6. No Access

    Article

    Are thiazolidinediones associated with an increased risk of heart failure and cardiovascular death?

    Paresh Dandona, Ajay Chaudhuri in Nature Clinical Practice Cardiovascular Medicine (2008)

  7. No Access

    Article

    Endothelial Dysfunction, Inflammation and Diabetes

    Paresh Dandona, Ahmad Aljada, Ajay Chaudhuri… in Reviews in Endocrine and Metabolic Disorde… (2004)

  8. No Access

    Article

    Optimal Treatment of Erectile Failure in Patients with Diabetes

    Erectile failure, although a common problem in male diabetic patients, is one of the most neglected complications of diabetes. The availability of drugs like alprostadil (prostaglandin E1; PGE1) and papaverine fo...

    Ajay Chaudhuri, Dr Philip G. Wiles in Drugs (1995)