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Article
Open AccessGss deficiency causes age-related fertility impairment via ROS-triggered ferroptosis in the testes of mice
Glutathione synthetase (GSS) catalyzes the final step in the synthesis of glutathione (GSH), a well-established antioxidant. Research on the specific roles of the Gss gene during spermatogenesis remains limited d...
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Article
Open AccessRhoGDIα regulates spermatogenesis through Rac1/cofilin/F-actin signaling
Spermatogenesis is an extremely complex process, and any obstruction can cause male infertility. RhoGDIα has been identified as a risk of male sterility. In this study, we generate RhoGDIα knockout mice, and find...
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Article
Open AccessCorrection: High levels of unbound bilirubin are associated with acute bilirubin encephalopathy in post-exchange transfusion neonates
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Chapter
LC Securities Co., Ltd. and Eastern Gold Jade Co., Ltd. v. Yunnan **nglong Industry Co., Ltd. and Zhao X et al.
As provided in Article 21 of the Guarantee Law of the People's Republic of China (repealed in 2021; hereinafter referred to as Guarantee Law), the scope of suretyship liability assumed by the surety shall firstly...
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Chapter and Conference Paper
Cross-Cultural Communicative Competence Based on Computer Aided Testing
In recent years, cross-cultural communication has played an important role in language acquisition. Improving students’ cross-cultural communication skills has become one of the focus of language teaching. It ...
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Article
Open AccessHigh levels of unbound bilirubin are associated with acute bilirubin encephalopathy in post-exchange transfusion neonates
Although it is known that unbound bilirubin can enter the brain, there is little evidence of its association with the development of acute bilirubin encephalopathy. Here, we investigated this potential relatio...
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Article
Tprn is essential for the integrity of stereociliary rootlet in cochlear hair cells in mice
Tprn encodes the taperin protein, which is concentrated in the tapered region of hair cell stereocilia in the inner ear. In humans, TPRN mutations cause autosomal recessive nonsyndromic deafness (DFNB79) by an un...
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Article
Loss of liver kinase B1 causes planar polarity defects in cochlear hair cells in mice
The tumor suppressor gene liver kinase B1 (LKB1), also called STK11, encodes a serine/threonine kinase. LKB1 plays crucial roles in cell differentiation, proliferation, and polarity. In this study, LKB1 condit...
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Article
Open AccessLoss of Lysyl Oxidase-like 3 Attenuates Embryonic Lung Development in Mice
Lysyl oxidase-like 3 (LOXL3), a human disease gene candidate, is a member of the lysyl oxidase (LOX) family and is indispensable for mouse palatogenesis and vertebral column development. Our previous study sho...
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Article
Open AccessLKB1 Regulates Cerebellar Development by Controlling Sonic Hedgehog-mediated Granule Cell Precursor Proliferation and Granule Cell Migration
The Liver Kinase B1 (LKB1) gene plays crucial roles in cell differentiation, proliferation and the establishment of cell polarity. We created LKB1 conditional knockout mice (LKB1Atoh1 CKO) to investigate the func...
