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  1. Article

    Open Access

    Lysyl oxidase inhibits BMP9-induced osteoblastic differentiation through reducing Wnt/β-catenin via HIF-1a repression in 3T3-L1 cells

    Bone morphogenetic protein 9 (BMP9) is a promising growth factor in bone tissue engineering, while the detailed molecular mechanism underlying BMP9-oriented osteogenesis remains unclear. In this study, we inve...

    Jie Zhang, FangLin Ye, AiHua Ye, BaiCheng He in Journal of Orthopaedic Surgery and Research (2023)

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  2. Article

    Open Access

    Cancer-secreted exosomal miR-21-5p induces angiogenesis and vascular permeability by targeting KRIT1

    Cancer-secreted exosomes are critical mediators of cancer-host crosstalk. In the present study, we showed the delivery of miR-21-5p from colorectal cancer (CRC) cells to endothelial cells via exosomes increase...

    Qinglian He, Aihua Ye, Weibiao Ye, **aomin Liao, Guoqiang Qin… in Cell Death & Disease (2021)

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  3. No Access

    Article

    Platelet–lymphocyte ratio as a potential prognostic factor in gynecologic cancers: a meta-analysis

    Cancer-related inflammation plays an important role in tumor development and progression. Platelet–lymphocyte ratio (PLR) has been studied as a biomarker for prognosis in gynecologic cancers. But, the results ...

    Shanshan Jiang, Jiandong Liu, **angyi Chen… in Archives of Gynecology and Obstetrics (2019)