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Chapter
Skin Substitutes in Wound Healing and the Stimulatory Effects of Adipose-Derived Stem Cells for the Proliferation of Keratinocytes on Chitosan
In the field of tissue engineering and reconstruction, the development of efficient biomaterial is in high demand to achieve uncomplicated wound healing. Chronic wounds and excessive scarring are the major com...
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Article
Cementoblastic lineage formation in the cross-talk between stem cells of human exfoliated deciduous teeth and epithelial rests of Malassez cells
The purpose of this study was to evaluate the synergistic effect of epithelial rests of Malassez cells (ERM) and transforming growth factor-β1 (TGF-β1) on proliferation, cementogenic and osteogenic differentiatio...
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Article
Open AccessDiscovery of candidate genes for nonsyndromic cleft lip palate through genome-wide linkage analysis of large extended families in the Malay population
Nonsyndromic orofacial clefts are one of the most common birth defects worldwide. It occurs as a result of genetic or environmental factors. This study investigates the genetic contribution to nonsyndromic cle...
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Chapter
Amniotic Membrane in the Treatment of Burns
Burn wound dressing represents an important aspect of burn care. The various inherent features of amniotic membrane proved to be useful as it contributes towards the attributes of an ideal dressing. This biolo...
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Article
Open AccessIn vitro characterization of a chitosan skin regenerating template as a scaffold for cells cultivation
Chitosan is a marine-derived product that has been widely used in clinical applications, especially in skin reconstruction. The mammalian scaffolds derived from bovine and porcine material have many limitation...
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Article
Association of TGFβ1 and SMAD4 variants in the etiology of keloid scar in the Malay population
Keloid is a complex condition with environmental and genetic risk-contributing factors. Two candidate genes, TGFβ1 and SMAD4, located in the same signaling pathway are highly expressed in the keloid fibroblast ce...
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Article
Open AccessAntiproliferative effect of methanolic extraction of tualang honey on human keloid fibroblasts
Keloid is a type of scar which extends beyond the boundaries of the original wound. It can spread to the surrounding skin by invasion. The use of Tualang honey is a possible approach for keloid treatment. The ...
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Article
Open AccessWound contraction effects and antibacterial properties of Tualang honey on full-thickness burn wounds in rats in comparison to hydrofibre
Full-thickness burn wounds require excision and skin grafting. Multiple surgical procedures are inevitable in managing moderate to severe full-thickness burns. Wound bed preparations prior to surgery are neces...
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Article
Open AccessAntibacterial properties of tualang honey and its effect in burn wound management: a comparative study
The use of honey as a natural product of Apis spp. for burn treatment has been widely applied for centuries. Tualang honey has been reported to have antibacterial properties against various microorganisms, includ...
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Article
Open AccessThe antibacterial properties of Malaysian tualang honey against wound and enteric microorganisms in comparison to manuka honey
Antibiotic resistance of bacteria is on the rise, thus the discovery of alternative therapeutic agents is urgently needed. Honey possesses therapeutic potential, including wound healing properties and antimicr...