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  1. Article

    Open Access

    Variation in treatment and survival of older patients with non-metastatic breast cancer in five European countries: a population-based cohort study from the EURECCA Breast Cancer Group

    Older patients are poorly represented in breast cancer research and guidelines do not provide evidence based recommendations for this specific group. We compared treatment strategies and survival outcomes betw...

    Marloes G. M. Derks, Esther Bastiaannet, Mandy Kiderlen… in British Journal of Cancer (2018)

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  2. Article

    Open Access

    Association of microRNAs and pathologic response to preoperative chemotherapy in triple negative breast cancer: preliminary report

    Triple negative breast cancer (TNBC) has caught the attention of oncologists worldwide because of poor prognosis and paucity of targeted therapies. Gene pathways have been widely studied, but less is known abo...

    Agnieszka Kolacinska, Jan Morawiec, Wojciech Fendler… in Molecular Biology Reports (2014)

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  3. No Access

    Article

    Gene expression and pathologic response to neoadjuvant chemotherapy in breast cancer

    Pathologic complete response after neoadjuvant systemic treatment appears to be a valid surrogate for better overall survival in breast cancer patients. Currently, together with standard clinicopathologic asse...

    Agnieszka Kolacinska, Wojciech Fendler, Janusz Szemraj… in Molecular Biology Reports (2012)

  4. No Access

    Article

    The DNA-damaging potential of tamoxifen in breast cancer and normal cells

    Tamoxifen (TAM) is a non-steroidal anti-estrogen used widely in the treatment and chemoprevention of breast cancer. TAM treatment can lead to DNA damage, but the mechanism of this process is not fully understo...

    Katarzyna Wozniak, Agnieszka Kolacinska, Maria Blasinska-Morawiec… in Archives of Toxicology (2007)

  5. No Access

    Article

    Polymorphisms of the promoter regions of matrix metalloproteinases genes MMP-1 and MMP-9 in breast cancer

    Matrix metalloproteinases play a crucial role in the cancer invasion and metastasis, angiogenesis and tumorigenicity. A single guanine insertion – the 1G/2G polymorphism in the promoter of the matrix metallopr...

    Karolina Przybylowska, Anita Kluczna… in Breast Cancer Research and Treatment (2006)

  6. No Access

    Article

    Polymorphisms of the DNA Mismatch Repair Gene HMSH2 in Breast Cancer Occurence and Progression

    The response of the cell to DNA damage and its ability to maintain genomic stability by DNA repair are crucial in preventing cancer initiation and progression. Therefore, polymorphism of DNA repair genes may a...

    Tomasz Poplawski, Marek Zadrozny… in Breast Cancer Research and Treatment (2005)

  7. No Access

    Article

    Polymorphisms of the BRCA2 and RAD51 Genes in Breast Cancer

    We performed a case-control study (150 cases and 150 controls) to test the association between three polymorphisms in BRCA2 and RAD51 genes and breast cancer risk. Genotypes were determined in DNA from blood cell...

    Tomasz Sliwinski, Renata Krupa, Ireneusz Majsterek… in Breast Cancer Research and Treatment (2005)