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  1. Article

    Open Access

    Deubiquitinase USP47-stabilized splicing factor IK regulates the splicing of ATM pre-mRNA

    IK depletion leads to an aberrant mitotic entry because of chromosomal misalignment through the enhancement of Aurora B activity at the interphase. Here, we demonstrate that IK, a spliceosomal component, plays...

    Hye In Ka, Sunyi Lee, Sora Han, Ae Lee Jeong, Ji Young Park… in Cell Death Discovery (2020)

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  2. No Access

    Article

    IK-guided PP2A suppresses Aurora B activity in the interphase of tumor cells

    Aurora B activation is triggered at the mitotic entry and required for proper microtubule-kinetochore attachment at mitotic phase. Therefore, Aurora B should be in inactive form in interphase to prevent aberra...

    Sunyi Lee, Ae Lee Jeong, Jeong Su Park, Sora Han… in Cellular and Molecular Life Sciences (2016)