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  1. Article

    Open Access

    Extracellular Microenvironmental Change by B16F10 Melanoma-derived Proteins Induces Cancer Stem-like Cell Properties from NIH3T3 Cells

    Cancer stem-like cells (CSCs) can generate solid tumors through the properties of stem cells such as self-renewal and differentiation and they cause drug resistance, metastasis and recurrence. Therefore, estab...

    Soon Yong Park, Dong Gwang Lee, Ara Jo, Hyeongrok Choi, Joo Eon Lee in Scientific Reports (2019)

  2. Article

    Open Access

    Microgravity induces autophagy via mitochondrial dysfunction in human Hodgkin’s lymphoma cells

    Gravitational forces can impose physical stresses on the human body as it functions to maintain homeostasis. It has been reported that astronauts exposed to microgravity experience altered biological functions...

    Ae ** Jeong, Yoon Jae Kim, Min Hyuk Lim, Haeri Lee, Kumhee Noh in Scientific Reports (2018)

  3. Article

    Open Access

    Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathway

    Mutation of PPP2R1A has been observed at high frequency in endometrial serous carcinomas but at low frequency in ovarian clear cell carcinoma. However, the biological role of mutation of PPP2R1A in ovarian and en...

    Ae Lee Jeong, Sora Han, Sunyi Lee, Jeong Su Park, Yiling Lu in Scientific Reports (2016)