6 Result(s)
within
Adam Kuspa
English
Bioinformatics
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Article
Open AccessComparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum
The social amoebae (Dictyostelia) are a diverse group of Amoebozoa that achieve multicellularity by aggregation and undergo morphogenesis into fruiting bodies with terminally differentiated spores and stalk ce...
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Article
Open AccessNew components of the Dictyostelium PKA pathway revealed by Bayesian analysis of expression data
Identifying candidate genes in genetic networks is important for understanding regulation and biological function. Large gene expression datasets contain relevant information about genetic networks, but mining...
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Article
Open AccessConserved developmental transcriptomes in evolutionarily divergent species
Evolutionarily divergent organisms often share developmental anatomies despite vast differences between their genome sequences. The social amoebae Dictyostelium discoideum and Dictyostelium purpureum have similar...
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Article
Open AccessdictyExpress: a Dictyostelium discoideum gene expression database with an explorative data analysis web-based interface
Bioinformatics often leverages on recent advancements in computer science to support biologists in their scientific discovery process. Such efforts include the development of easy-to-use web interfaces to biom...
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Article
Open AccessHigh-throughput analysis of spatio-temporal dynamics in Dictyostelium
We demonstrate a time-lapse video approach that allows rapid examination of the spatio-temporal dynamics of Dictyostelium cell populations. Quantitative information was gathered by sampling life histories of more...
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Article
The promise of a protist: the Dictyostelium genome project
The genome of Dictyostelium discoideum is being sequenced by an international consortium and is scheduled for completion in the next few years. The sequence will accelerate research into a number of phenomena ca...
