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Article
Muscle strength and osteoarthritis of the knee: a systematic review and meta-analysis of longitudinal studies
To evaluate the sex-specific association between low knee extensor and flexor muscle strength and the risk of knee structural worsening.
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Article
Open AccessImmediate and Delayed Effects of Joint Loading Activities on Knee and Hip Cartilage: A Systematic Review and Meta-analysis
The impact of activity-related joint loading on cartilage is not clear. Abnormal loading is considered to be a mechanical driver of osteoarthritis (OA), yet moderate amounts of physical activity and rehabilita...
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Article
Open AccessAn anti-inflammatory diet intervention for knee osteoarthritis: a feasibility study
Knee osteoarthritis has an inflammatory component that is linked to pain and joint pathology, yet common non-surgical and non-pharmacological interventions (e.g., exercise, calorie restricting diets) do not ty...
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Article
Open AccessExercise-therapy and education for individuals one year after anterior cruciate ligament reconstruction: a pilot randomised controlled trial
Guided rehabilitation beyond 6-months is rare following anterior cruciate ligament reconstruction (ACLR), despite high prevalence of unacceptable symptoms and quality of life (QoL). Our primary aim was to dete...
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Article
Greater knee flexion excursion/moment in hop** is associated with better knee function following anterior cruciate ligament reconstruction
Individuals with impaired knee function after anterior cruciate ligament reconstruction (ACLR) may be at greater risk of develo** knee osteoarthritis related to abnormal knee joint movement and loading. The ...
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Article
Lateral displacement, sulcus angle and trochlear angle are associated with early patellofemoral osteoarthritis following anterior cruciate ligament reconstruction
Patellofemoral osteoarthritis (PFOA) occurs in approximately half of anterior cruciate ligament (ACL)-injured knees within 10–15 years of trauma. Risk factors for post-traumatic PFOA are poorly understood. Pat...
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Article
Poor knee function after ACL reconstruction is associated with attenuated landing force and knee flexion moment during running
Poor knee function after anterior cruciate ligament reconstruction (ACLR) may increase the risk of future knee symptoms and knee osteoarthritis via abnormal knee joint loading patterns, particularly during hig...
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Article
Open AccessValidation of an active shape model-based semi-automated segmentation algorithm for the analysis of thigh muscle and adipose tissue cross-sectional areas
To validate a semi-automated method for thigh muscle and adipose tissue cross-sectional area (CSA) segmentation from MRI.
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Article
Defining the presence of radiographic knee osteoarthritis: a comparison between the Kellgren and Lawrence system and OARSI atlas criteria
The Kellgren and Lawrence (K/L) system and Osteoarthritis Research Society International (OARSI) atlas are frequently used to define radiographic knee osteoarthritis (OA). The purpose of the current study was ...
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Article
Open AccessDown on one knee: soft tissue knee injuries across the lifespan
Joint injury is a potent risk factor for osteoarthritis, the most important musculoskeletal disease affecting humankind. Yet the population incidence of soft tissue knee injury is not well documented. Using he...