-
Article
Open AccessIdentification of cerebrospinal fluid and serum metabolomic biomarkers in first episode psychosis patients
Psychotic disorders are currently diagnosed by examining the patient’s mental state and medical history. Identifying reliable diagnostic, monitoring, predictive, or prognostic biomarkers would be useful in cli...
-
Article
Open AccessGenetic contributions to alcohol use disorder treatment outcomes: a genome-wide pharmacogenomics study
Naltrexone can aid in reducing alcohol consumption, while acamprosate supports abstinence; however, not all patients with alcohol use disorder (AUD) benefit from these treatments. Here we present the first gen...
-
Article
Open AccessGenetic variant in SLC1A2 is associated with elevated anterior cingulate cortex glutamate and lifetime history of rapid cycling
Glutamatergic dysregulation is implicated in the neurobiology of mood disorders. This study investigated the relationship between the anterior cingulate cortex (AC) glutamate, as measured by proton magnetic re...
-
Article
Open AccessBipolar disorder with binge eating behavior: a genome-wide association study implicates PRR5-ARHGAP8
Bipolar disorder (BD) is associated with binge eating behavior (BE), and both conditions are heritable. Previously, using data from the Genetic Association Information Network (GAIN) study of BD, we performed ...
