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Article
Induction of the IL-13 receptor α2-chain by IL-4 and IL-13 in human keratinocytes: involvement of STAT6, ERK and p38 MAPK pathways
IL-4 and IL-13 are related cytokines which induce both pro- and anti-inflammatory effects depending on the cell type they act upon and the nature of the receptors expressed. The type I receptor complex is comp...
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Chapter and Conference Paper
Monoclonal Antibody AB1 Identifies a Human B Cell Activation Antigen and Inhibits Growth Factor-Dependent Human B Cell Proliferation
In both human and animal systems, various growth factors have been shown to be involved in B cell proliferation and differentiation (reviewed in Ref. 1). B cell growth factor (BCGF), also named B cell stimulat...
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Chapter
Human Immunoregulatory Molecules: Interleukin 1, Interleukin 2. and B-Cell Growth Factor
Intensive investigations over the past several years have clearly indicated that a significant degree of immune regulation is accomplished by soluble mediators. Among the host of potential immune regulators th...
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Article
Soluble factor activation of human B lymphocytes
Medium conditioned by lectin (and/or antigen)-stimulated human peripheral blood lymphocytes has been shown to contain factors, termed interleukin 1 (IL-1) and interleukin 2 (IL-2)1,2, which augment and maintain h...