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  1. No Access

    Article

    Trimetazidine Preconditioning Potentiates the Effect of Mesenchymal Stem Cells Secretome on the Preservation of Rat Pancreatic Islet Survival and Function In Vitro

    Islet transplantation offers improved glycemic control in individuals with type 1 diabetes mellitus. However, in vitro islet culture is associated with islet apoptosis and eventually will lose their functional...

    Fariborz Ahmadi, Abbas Sahebghadam Lotfi… in Applied Biochemistry and Biotechnology (2023)

  2. No Access

    Article

    Comparison of transduction efficiency among various cell types by a lentivector containing CMV promoter

    Due to their unique biological characteristics, mesenchymal stem cells (MSCs) are useful in develo** cell-based therapies, tissue regeneration, and many other applications of cellular and molecular genetics....

    Hori Ghaneialvar, Abbas Sahebghadam Lotfi, Sareh Arjmand… in Comparative Clinical Pathology (2019)

  3. No Access

    Article

    Characterization and Classification of Mesenchymal Stem Cells in Several Species Using Surface Markers for Cell Therapy Purposes

    Mesenchymal stem cells are multipotent cells capable of replicating as undifferentiated cells, and have the potential of differentiating into mesenchymal tissue lineages such as osteocytes, adipocytes and chon...

    Hori Ghaneialvar, Leila Soltani… in Indian Journal of Clinical Biochemistry (2018)

  4. No Access

    Article

    Survey of Omp19 immunogenicity against Brucella abortus and Brucella melitensis: influence of nanoparticulation versus traditional immunization

    Brucellosis is the most common zoonotic bacterial disease. Prevention of human brucellosis is achieved through pasteurization of dairy products, appropriate sanitation and vaccination of domestic animals again...

    Morteza Abkar, Abbas Sahebghadam Lotfi, Jafar Amani… in Veterinary Research Communications (2015)

  5. No Access

    Article

    Alpha 1-antitrypsin activity is markedly decreased in Wegener’s granulomatosis

    Alpha 1-antitrypsin (A1AT) is the most abundant proteinase inhibitor in plasma and the main inhibitor of Proteinase 3, the target antigen of antineutrophil cytoplasmic antibodies (ANCAs) that predominant in We...

    Ali Mota, Abbas Sahebghadam Lotfi, Ahmad-Reza Jamshidi… in Rheumatology International (2014)

  6. Article

    Open Access

    The design of a new truncated and engineered alpha1-antitrypsin based on theoretical studies: an antiprotease therapeutics for pulmonary diseases

    Alpha 1- antitrypsin (α1AT) a 54 kDa glycoprotein is a protease inhibitor. In the absence of α1AT, elastase released by lung macrophages, was not inhibited and lead to elastin breakdown and pulmonary problems ...

    Nazanin Pirooznia, Sadegh Hasannia… in Theoretical Biology and Medical Modelling (2013)

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  7. Article

    Open Access

    Encapsulation of Alpha-1 antitrypsin in PLGA nanoparticles: In Vitro characterization as an effective aerosol formulation in pulmonary diseases

    Alpha 1- antitrypsin (α1AT) belongs to the superfamily of serpins and inhibits different proteases. α1AT protects the lung from cellular inflammatory enzymes. In the absence of α1AT, the degradation of lung ti...

    Nazanin Pirooznia, Sadegh Hasannia, Abbas Sahebghadam Lotfi… in Journal of Nanobiotechnology (2012)

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