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    Modulators of the Nrf2 Signaling Pathway Enhance the Cytotoxic Effect of Standard Chemotherapeutic Drugs on Organoids of Metastatic Colorectal Cancer

    The activity of known modulators of the Nrf2 signaling pathway (bardoxolone and brusatol) was studied on cultures of tumor organoids of metastatic colorectal cancer previously obtained from three patients. The...

    A. V. Razumovskaya, M. O. Silkina in Bulletin of Experimental Biology and Medic… (2024)

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    Assessing the Efficacy of Anti-Cancer Drugs on Organoid Models Derived from Prostate Cancer

    It was proven that tumor organoids effectively mirror the phenotypic and genetic traits of the original biomaterial. It was reported that outcomes from drug testing in organoid cultures can accurately represen...

    M. O. Silkina, A. V. Razumovskaya, S. V. Nikulin in Doklady Biochemistry and Biophysics (2023)

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    Biogeochemical Migration and Accumulation of Chemical Elements by Plants in the Aquatic System of the Discharge Channel of the Kola NPP

    Full major- and trace-element composition of water and selected higher aquatic plants in the discharge channel of the Kola NPP was determined using the inductively-coupled plasma mass spectrometry. The water q...

    I. R. Elizarova, D. S. Bernadskaya, D. B. Denisov in Geochemistry International (2022)

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    Metal micro- and nanowires fabricated by matrix synthesis and their application in mass spectrometry

    Cylindrical and conical micro- and nanowires were fabricated by matrix (template) synthesis in pores of track membranes. A technique for filling matrix pores with metal (copper, nickel, and silver) was develop...

    S. A. Bedin, O. G. Rybalko, N. B. Polyakov in Inorganic Materials: Applied Research (2010)