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Article
Characterization of proliferative effects of insulin, insulin analogues and insulin-like growth factor-1 (IGF-1) in human lung fibroblasts
Insulin has been approved for inhaled application, but safety concerns remain, because of un-physiologically high insulin concentrations in the lung. Since insulin may act as growth factor, possible proliferat...
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Chapter
Regulation of Cell Growth by the Myc-Max-Mad Network: Role of Mad Proteins and YY1
Since the discovery of the c-Myc dimerization partner Max (Blackwood and Eisenman 1991; Prendergast et al. 1991) a startling number of proteins capable to interact directly or indirectly with c-Myc and/or Max ...
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Article
Maternal but not paternal transmission of 15q11–13–linked nondeletion Angelman syndrome leads to phenotypic expression
Angelman syndrome (AS) may result from either maternally inherited deletions of chromosome 15q11–13 or from paternal uniparental disomy for chromosome 15. This is in contrast to Prader–Willi syndrome (PWS), wh...