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Article
Open AccessErratum to: Home-based palliative approach for people with severe multiple sclerosis and their carers: study protocol for a randomized controlled trial
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Article
Individualized quality of life of severely affected multiple sclerosis patients: practicability and value in comparison with standard inventories
Individualized quality of life (QoL) measures differ from traditional inventories in that QoL domains/weights are not predetermined, but identified by the individual. We assessed practicability of the Schedule...
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Article
Open AccessErratum to: ‘Home-based palliative approach for people with severe multiple sclerosis and their carers: study protocol for a randomized controlled trial’
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Chapter
Scelta della terapia: Valore e utilità di un approccio condiviso
Un’adeguata informazione e partecipazione dei pazienti ai processi decisionali, oltre a essere un imperativo etico, comporta effetti positivi misurabili e rilevanti, come una maggiore aderenza alle prescrizion...
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Article
Intense immunosuppression followed by autologous stem cell transplantation in severe multiple sclerosis
Aggressive forms of multiple sclerosis (MS) represent a limited group of demyelinating diseases that rapidly progress to severe disability. Currently available therapies are poorly effective against these clin...
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Article
Local drug delivery in recurrent malignant gliomas
In recurrent malignant gliomas, we scheduled a protocol by adding to systemic temozolomide a local treatment delivered through a reservoire positioned in the surgically created cavity, consisting of either mit...
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Article
Disability in young patients suffering from primary headaches
During the last decade researchers have begun to employ standardised methodologies to investigate the global impact of primary headaches. Disease-specific instruments have been developed to measure headache-re...
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Article
Measuring responses to therapy in headache patients: new and traditional end-points
Changes in numerical indices of the intensity, duration and frequency of attacks are traditionally used to assess the effectiveness of treatments for migraine and other primary headaches. However, recent clini...
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Article
Disability and quality of life in different primary headaches: results from Italian studies
Headaches may have a wide range of impact on patients’ lives. We report the results of Italian studies in which disability and health-related quality of life (HRQOL) in patients with different primary headache...
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Article
General practitioners facing dementia: are they fully prepared?
We assessed knowledge about Alzheimer’s disease (AD) in a sample of Italian general practitioners (GPs). We first carried out a propedeutic study to verify the ability of an Italian version of the University o...
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Article
Italian version of the Chicago multiscale depression inventory: translation, adaptation and testing in people with multiple sclerosis
Depression is the commonest psychiatric disturbance in people with multiple sclerosis (MS), with prevalence higher than in the general population and other chronic diseases. However, accurate assessment of dep...
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Article
Quality of life and disability in primary chronic daily headaches
We assessed functional disability and health-related quality of life (HRQOL) in Italian patients suffering from chronic migraine and medication overuse (150 subjects) or chronic cluster headache (22 subjects)...
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Article
Health status of people with multiple sclerosis: a community mail survey
We assessed the self-perceived health status of people with multiple sclerosis (MS) living in the Province of Milan, and the consequences of the disease on family, social and occupational status, using a cros...
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Article
Chronic inflammatory demyelinating polyradiculoneuropathy: long-term course and treatment of 60 patients
The objective of this study was to assess the long-term course and treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). We evaluated, according to a predefined protocol, a series of ...
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Article
Relation of cognitive impairment and depression to quality of life in multiple sclerosis patients
The objectives of the present study were to determine the role of cognitive and mood disorders as determinants of health-related quality of life (HRQOL) in multiple sclerosis (MS), as well as to evaluate the v...
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Article
Affective disorders and multiple sclerosis: a controlled study on 65 Italian patients
A high prevalence of major mood disorders in multiple sclerosis (MS) patients has been reported. In this study, we investigated the frequency of previous or present major mood disorders in 65 patients with cli...
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Article
A multicenter Italian randomised study on early treatment of Parkinson disease: comparison of 1-dopa, 1-deprenyl and dopaminoagonists. Study design and short term results
On the long term Parkinson Disease (PD) treatment is often complicated by the occurrence of motor fluctuations. To find out whether early treatment of PD with levodopa, dopaminoagonists or 1-deprenyl is associ...
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Chapter
Studies on the Initiation of DNA Synthesis in Plant and Animal Cells
DNA dependent DNA polymerases (E. C. 2. 7. 7. 7) play a key role in DNA replication by copying with high efficiency and fidelity the appropriate templates. These enzymes are, however, unable to initiate DNA sy...
