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  1. No Access

    Article

    A novel bivalent anti-c-MET/PD-1 bispecific antibody exhibits potent cytotoxicity against c-MET/PD-L1-positive colorectal cancer

    Previously, we generated a novel bispecific antibody (BsAb) simultaneously targeting both c-MET and PD-1 (PDCD1), which can bridge T cells and c-MET positive tumor cells. However, the specific mechanisms and a...

    Z. Sun, C. Gu, X. Wang, A. Shang, W. Quan, J. Wu, P. Ji… in Investigational New Drugs (2023)

  2. No Access

    Article

    MiR-495-3p and miR-143-3p co-target CDK1 to inhibit the development of cervical cancer

    The GEO database and KEGG database-based analyses identified the differential expression of cyclin-dependent kinase 1 (CDK1) in cervical cancer and its involvement in the cell cycle pathway. In the present stu...

    J. Tang, H. Pan, W. Wang, C. Qi, C. Gu, A. Shang… in Clinical and Translational Oncology (2021)