9 Result(s)
within
A. Rosenthal
Oncology
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Chapter
Case 24. Extranodal NK/T-Cell lymphoma, nasal type
NK/T-cell lymphomas are extremely rare lymphomas in the western world. The population of CD3+CD56+ NK/T-cells that seems to be the progenitor cells for those types of lymphomas is not homogeneous, which may ex...
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Article
Open AccessFlow cytometry defined cytoplasmic immunoglobulin index is a major prognostic factor for progression of asymptomatic monoclonal gammopathies to multiple myeloma (subset analysis of SWOG S0120)
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Article
Clinical value of molecular subty** multiple myeloma using gene expression profiling
Using a data set of 1217 patients with multiple myeloma enrolled in Total Therapies, we have examined the impact of novel therapies on molecular and risk subgroups and the clinical value of molecular classific...
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Article
Open AccessCarfilzomib and the cardiorenal system in myeloma: an endothelial effect?
Carfilzomib (Cfz) has been associated with an ~5% incidence of unexplained and unpredictable cardiovascular toxicity in clinical trials. We therefore implemented a detailed, prospective, clinical cardiac and r...
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Article
Open AccessThe flow cytometry-defined light chain cytoplasmic immunoglobulin index and an associated 12-gene expression signature are independent prognostic factors in multiple myeloma
As part of Total Therapy (TT) 3b, baseline marrow aspirates were subjected to two-color flow cytometry of nuclear DNA content and cytoplasmic immunoglobulin (DNA/CIG) as well as plasma cell gene expression pro...
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Article
Open AccessRenal insufficiency retains adverse prognostic implications despite renal function improvement following Total Therapy for newly diagnosed multiple myeloma
Renal insufficiency (RI) is a frequent complication of multiple myeloma (MM) with negative consequences for patient survival. The improved clinical outcome with successive Total Therapy (TT) protocols was limi...
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Article
Frequent allelic loss of the BCL10 gene in lymphomas with the t(11;14)(q13;q32)
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Article
Open AccessA comparison of national cancer registry and direct follow-up in the ascertainment of ovarian cancer
The National Health Service Central Register (NHSCR) and direct follow-up were used to document ovarian and fallopian tube cancers in 22 000 women from 1986 to 1993. Direct follow-up identified 47/49 cases (96...
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Article
Solitary myeloblastoma presenting as acute hydrocephalus: review of literature, implications for therapy
An unusual presentation of a case of myeloblastoma (granulocystic sarcoma, chloroma) as demonstrated by computed tomography (CT) and selective angiography is reported. Our patient, who presented with acute hyd...
