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Article
Persistent orthostatic headache without intracranial hypotension: which treatment?
Orthostatic headache can be the leading symptom of intracranial hypotension, however, not all orthostatic headaches are due to cerebrospinal fluid leaks and these forms can be a clinical problem, especially fo...
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Article
Difficulties in work activities and the pervasive effect over disability in patients with episodic and chronic migraine
Migraine is associated with reduced productivity in work-related activities. The degree to which problems with work are, in turn, associated to the level of migraine-related disability as well as to headache f...
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Article
Prevalence and profile of obsessive–compulsive trait in patients with chronic migraine and medication overuse
Patients with chronic migraine (CM) and medication overuse headache (MOH) have high frequency of psychiatric comorbidity or psychopathological traits, the presence of which can influence the clinical course. T...
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Article
Occipital neurostimulation in primary headaches: update
A subset of headache patients are chronic and results refractory to standard medical treatments, they are unsatisfied or unable to tolerate the side effects of medications. In the lack of more effective prophy...
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Article
Outcome of patients with chronic migraine with medication overuse and depression after duloxetine: influence of coexisting obsessive compulsive disorder
Patients with chronic migraine (CM) and medication overuse (MO) have high frequency of psychiatric comorbidity. Aims of this open label, prospective, independent study were: to evaluate the efficacy of duloxet...
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Article
Positive outcome of occlusal freeway space reestablishment in patients with medication overuse due to chronic migraine
Considering the great chapter of migraines, it is important to note the signs and symptoms caused by an alteration of the relationship of the facial musculature and the occlusal freeway space (FWS) that is the...
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Article
Drug-resistant chronic migraine: the Italian GON project
Chronic daily headache is a major problem due to severe disability and high socio-economic costs. In the last years, some trials have shown potential benefit from new therapeutic approach by occipital neurosti...
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Article
Treatment of alterations in CSF dynamics
Alterations of the intracranial pressure (ICP) may be present in several conditions. The aim of this brief review is to focus on two relatively rare conditions characterized by alterations in cerebro-spinal fl...
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Article
Polytherapy for the prophylaxis of chronic migraine: an Italian survey
Chronic migraine (CM) represents an important medical issue, due to morbidity, high disability, presence of comorbidities, and medication overuse (MO). The prophylaxis of CM has not been extensively explored s...
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Article
Psychopathological profile of patients with chronic migraine and medication overuse: study and findings in 50 cases
Patients with chronic migraine (CM) have high frequence of psychiatric comorbidity or psychological distress. The presence of depression, anxiety, panic or obsessive disorders in these patients contributes to ...
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Article
Costs of hypothalamic stimulation in chronic drug-resistant cluster headache: preliminary data
In about 20% of chronic cluster headache (CH) cases, drugs may become ineffective. Under these circumstances, steroids and triptans are frequently employed leading to fearful side effects in one and high costs...
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Article
Feasibility of simultaneous vagal nerve and deep brain stimulation in chronic cluster headache: case report and considerations
In pathologies, such as refractory epilepsy, major depression and cluster headache, there could be indication to both vagal nerve stimulation (VNS) and deep brain stimulation (DBS). In particular, Mauskop (Cep...
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Article
Painful ophthalmoplegia: a retrospective study of 23 cases
Painful ophthalmoplegia is a rare pathologic condition caused by non-specific inflammation of the cavernous sinus, but other causes such as tumours, vasculitis, basal meningitis, neurosarcoidosis, diabetes can...
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Chapter
Cefalea a grappolo e TACs: la clinica
Le forme di cefalea di lunga durata quali l’emicrania e la cefalea tensiva, costituiscono il gruppo di più frequente riscontro nella pratica clinica. Le cefalee di breve durata sono meno frequenti ma vanno ugu...
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Article
Functional neuroimaging and headache pathophysiology: new findings and new prospects
In the last ten years pathophysiology of primary headaches has received new insights from neuroimaging studies. Positron emission tomography (PET) showed activation of specific brain structures, brainstem in m...
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Article
Deep brain stimulation in craniofacial pain: seven years' experience
Cluster headache (CH) is a primary headache with excruciatingly painful attacks that are strictly unilateral. About 10% of cases experience no significant remission, and about 15% of these do not respond to me...
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Article
Neuroimaging and pain: a window on the autonomic nervous system
Pain is one of the most common experiences of humans. Neuroimaging techniques can visualize the main brain areas involved in pain modulation, the pain matrix. It is noteworthy that many of the brain areas form...
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Article
Neurophysiological approach to the study of cluster headache