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Article
Multicellular Mathematical Modelling of Mesendoderm Formation in Amphibians
The earliest cell fate decisions in a develo** embryo are those associated with establishing the germ layers. The specification of the mesoderm and endoderm is of particular interest as the mesoderm is induc...
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Article
Wave pinning and spatial patterning in a mathematical model of Antivin/Lefty–Nodal signalling
Nodal signals are key regulators of mesoderm and endoderm development in vertebrate embryos. It has been observed experimentally that in Xenopus embryos the spatial range of Nodal signals is restricted by the sig...
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Article
Mathematical Modelling of the Aux/IAA Negative Feedback Loop
The hormone auxin is implicated in regulating a diverse range of developmental processes in plants. Auxin acts in part by inducing the Aux/IAA genes. The associated pathway comprises multiple negative feedback lo...
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Article
Evaluation of a commercial radiometric system for primary isolation of mycobacteria over a fifteen-year period
The rate of recovery and time to detection of mycobacteria from clinical specimens were analysed for specimens inoculated into both radiometric Middlebrook 7H12 (Bactec 12B, originally 12A) medium and Lowenste...