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  1. Article

    Open Access

    Elevated soluble TNFα levels and upregulated TNFα mRNA expression in purified peripheral blood monocyte subsets associated with high-grade hepatocellular carcinoma

    Chronic inflammation is involved in the initiation and progression of various cancers, including liver cancer. The current study focuses on the characterization of the peripheral immune response in hepatocellu...

    C. Martín-Sierra, R. Martins, M. Coucelo, A. M. Abrantes… in Journal of Inflammation (2020)

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  2. No Access

    Article

    Oxidative Stress, DNA, Cell Cycle/Cell Cycle Associated Proteins and Multidrug Resistance Proteins: Targets of Human Amniotic Membrane in Hepatocellular Carcinoma

    The anticancer effects of human amniotic membrane (hAM) have been studied over the last decade. However, the action mechanisms responsible for these effects are not fully understood until now. Previously resul...

    A. C. Mamede, S. Guerra, M. Laranjo, K. Santos… in Pathology & Oncology Research (2016)

  3. No Access

    Article

    Selective cytotoxicity and cell death induced by human amniotic membrane in hepatocellular carcinoma

    Hepatocellular carcinoma (HCC) has a worldwide high incidence and mortality. For this reason, it is essential to invest in new therapies for this type of cancer. Our team already proved that human amniotic mem...

    A. C. Mamede, S. Guerra, M. Laranjo, M. J. Carvalho, R. C. Oliveira… in Medical Oncology (2015)

  4. No Access

    Article

    Revisit dietary fiber on colorectal cancer: butyrate and its role on prevention and treatment

    Colorectal cancer is still a major health problem worldwide. Based on the most recent released data by the World Health Organization GLOBOCAN in 2012, colorectal cancer is the third most prevalent type of canc...

    J. C. Encarnação, A. M. Abrantes, A. S. Pires… in Cancer and Metastasis Reviews (2015)

  5. No Access

    Article

    Effect of Amniotic Membrane Proteins in Human Cancer Cell Lines: An Exploratory Study

    Human amniotic membrane (hAM) has recently drawn attention as an upcoming anti-cancer therapy. Regarding the strategies which have already investigated, little is known about hAM protein extracts (hAMPE) effec...

    Ana Catarina Mamede, M. Laranjo, M. J. Carvalho… in The Journal of Membrane Biology (2014)

  6. No Access

    Article

    Amniotic membrane: from structure and functions to clinical applications

    Amniotic membrane (AM) or amnion is a thin membrane on the inner side of the fetal placenta; it completely surrounds the embryo and delimits the amniotic cavity, which is filled by amniotic liquid. In recent y...

    A. C. Mamede, M. J. Carvalho, A. M. Abrantes, M. Laranjo… in Cell and Tissue Research (2012)