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Article
The role of biochemical of bone turnover markers in osteoporosis and metabolic bone disease: a consensus paper of the Belgian Bone Club
The exact role of biochemical markers of bone turnover in the management of metabolic bone diseases remains a topic of controversy. In this consensus paper, the Belgian Bone Club aimed to provide a state of th...
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Article
Controversy about the relative efficacy of dipeptidyl peptidase IV inhibitors
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Article
Rôle de l’enzyme 11β-hydroxystéroïde-déshydrogénase de type 1 dans le risque métabolique associé à l’obésité
Certaines similitudes entre le syndrome métabolique associé à l’obésité abdominale et le syndrome de Cushing ont fait rechercher un excès tissulaire en glucocorticoïdes, même en l’absence de taux anormalement ...
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Article
Rosiglitazone: to be or not to be?
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Article
Sujets « métaboliquement sains », bien qu’obèses. Deuxième partie : pronostic et prise en charge
Environ 30 à 50 % des sujets sont « métaboliquement sains » bien qu’ils soient obèses (MHO pour metabolically healthy, but obese) alors qu’inversement, nombre de sujets non obèses sont « métaboliquement anormaux ...
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Article
Sujets « métaboliquement sains », bien qu’obèses. Première partie: diagnostic, physiopathologie et prévalence
Environ 30 à 50 % des sujets obèses sont « métaboliquement normaux » (MHO metabolically healthy, but obese) alors qu’inversement, nombre de sujets non obèses sont « métaboliquement anormaux ». La topographie et l...
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Article
Sujets « métaboliquement obèses » de poids normal. Seconde partie: pronostic et prise en charge
Les personnes non obèses « métaboliquement anormales » (MONW) sont rarement dépistées en raison d’un poids corporel faussement rassurant. Elles présentent pourtant bon nombre de marqueurs du syndrome métaboliq...
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Article
Sujets « métaboliquement obèses » de poids normal. Première partie: diagnostic, physiopathologie et prévalence
L’obésité, notamment abdominale, est le facteur de risque principal du syndrome métabolique. Cependant, il existe manifestement des personnes non obèses qui sont métaboliquement anormales et, donc, vraisemblab...
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Article
40th EASD Annual Meeting of the European Association for the Study of Diabetes
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Article
Intact cross-talk between insulin secretion and insulin action after postgastroplasty recovery of ideal body weight in severely obese patients
Most reports investigating the hormonal and metabolic effects of bariatric surgery studied obese subjects after partial weight loss only. Nevertheless, all studies showed significant improvements of insulin se...
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Article
35th Annual Meeting of the European Association for the Study of Diabetes
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Article
Plasma leptin levels, insulin secretion, clearance and action on glucose metabolism in anorexia nervosa
From a metabolic point of view, anorexia nervosa may be viewed as a mirror image of obesity. We compared insulin secretion, clearance and action on glucose metabolism during an intravenous glucose tolerance te...
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Article
Alterations in the ultradian oscillations of insulin secretion and plasma glucose in aging
Normal insulin secretion includes oscillations with a period length of 80–150 min which are tightly coupled to glucose oscillations of similar period. To determine whether normal aging is associated with alter...
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Chapter
Pulsatility of Glucagon
As reviewed elsewhere (Lefèbvre et al. 1987), various observations made in vivo and in vitro have shown that glucagon secretion is not a continuous, but rather a pulsatile, process. Furthermore, administration of...
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Chapter
The Glucagon Test for Evaluation of Insulin Secretion
Insulin secretion plays a key role in the homeostasis of blood glucose levels and may be altered in numerous pathological states. It is thus important to have appropriate methods for evaluating insulin secreti...
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Chapter
Glucagonoma and Its Management
Glucagonomas are considered to be among the rarest of the islet-cell tumors, with approximately 200 cases reported to date, even though they may be underdiagnosed clinical entities (Edey et al. 1990). Because of ...
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Chapter
Pathophysiology of Type 2 Diabetes Mellitus
Non-insulin-dependent diabetes mellitus (NIDDM), also called type 2 diabetes mellitus, is a common metabolic disorder that afflicts 2%–5% of the adult population of most Western countries, with, however, wide ...
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Article
Availability of glucose ingested during muscle exercise performed under acipimox-induced lipolysis blockade
This study investigated the percentage of carbohydrate utilization than can be accounted for by glucose ingested during exercise performed after the ingestion of the potent lipolysis inhibitor Acipimox. Six he...
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Article
Sandostatin, a new analogue of somatostatin, reduces the metabolic changes induced by the nocturnal interruption of continuous subcutaneous insulin infusion in Type 1 (insulin-dependent) diabetic patients
With the aim of assessing a new somatostatin analogue to prevent the metabolic changes induced by a 6-h nocturnal arrest of an insulin pump, nine C-peptide negative Type 1 (insulin-dependent) diabetic patients...
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Article
Impaired insulin-induced erythrocyte magnesium accumulation is correlated to impaired insulin-mediated glucose disposal in Type 2 (non-insulin-dependent) diabetic patients
Plasma and erythrocyte magnesium levels were measured by atomic absorption spectrometry in 12 healthy subjects and 12 moderately obese patients with Type 2 (non-insulin-dependent) diabetes mellitus. Basal plas...
